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New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

Mycorrhizal Interactions Influences Global Forest Diversity Patterns and Structure

Recent research published in Nature Communications Biology adds to the increasing understanding of the disproportionate impact that microbes have on everything from crop yields to human digestion: Global forest diversity appears to be influenced by microbes in the soil, in this case, fungi.

8 Jan 2024

Scientists Discover How Brain's "Population Clock" Guides Behavior

From Aristotle's musings on the nature of time to Einstein's theory of relativity, humanity has long pondered: how do we perceive and understand time? The theory of relativity posits that time can stretch and contract, a phenomenon known as time dilation. Just as the cosmos warps time, our neural circuits can stretch and compress our subjective experience of time. As Einstein famously quipped, "Put your hand on a hot stove for a minute, and it seems like an hour. Sit with a pretty girl for an hour, and it seems like a minute".

14 Jul 2023

Significance of astrocyte–neuron interactions in fine-tuning brain function

Humans learn to handle a variety of skilled movements throughout their lives, from driving a car to swinging a tennis racket. Neurons are not the only ones who implement this learning, but a new study from The Picower Institute for Learning and Memory at MIT shows that astrocytes play an important role as well.

From Massachusetts Institute of Technology (MIT) 14 Mar 2023

Researchers find an epigenetic adaptation showing resistance to targeted therapy in T cell leukemia

Although gene mutations can result in drug resistance, scientists in the Perelman School of Medicine at the University of Pennsylvania have found a vital, non-genetic version that could also boost resistance to targeted treatment in T cell leukemia, which is a kind of blood cell cancer.

3 Mar 2022

New microscopy method to observe the movement of fast biological processes in 3D

Scientists have come up with a method that enables the use of multi-focal images to reconstruct the movement of fast biological processes in 3D.

29 Jul 2021

Scientists generate a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

25 Mar 2021

Study: Phase separated droplets have many important functions in cells

Autophagy is a fundamental cellular process by which cells capture and degrade their own dysfunctional or superfluous components for degradation and recycling.

22 Jan 2021