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Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands

Scientists Discover New Pathway for Biosynthesis of Cardenolides in Plants

Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants.

19 Sep 2023

Hormone Testosterone Alters Electric Fish's Ability to Ignore Its Own Signals

During the rainy breeding season, the underwater "conversation" among electric fish changes. Fish revved up to make a match broadcast slightly different signals to advertise their presence and identify compatible mates.

17 Aug 2023

Discovering Age and Sex-Specific Obesity Genes in the Genome

Right from impacting how the human body stores fat to how the brain regulates appetite, hundreds of genes, together with environmental factors, jointly identify weight and body size.

3 Aug 2023

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

Prime Target for Male Contraceptive Development Identified

As far as a highly effective, reversible, and non-hormonal male contraceptive for humans and animals is concerned, the discovery of a gene in multiple mammalian species could set the stage.

18 Apr 2023

Identifying biomarkers that help treat fatty liver patients with a personalized diet

Recent research from the University of Jyväskylä contrasted the gut microbiota and gut-derived metabolites of healthy controls and fatty liver patients. The findings show that some microbial metabolites are linked to liver fat content.

23 Mar 2023

Potential approach for mitigating ALS pathogenesis

Every year, 5,000 people in the United States are diagnosed with ALS, an incurable neurodegenerative disease that will destroy them within two to five years.

8 Feb 2023

Regulating cholesterol production with novel protein

Everyone must have heard about cholesterol and how important it is to eat heart-healthy meals to keep it under control.

From The University of New South Wales (UNSW) 8 Nov 2022

Dads' close involvement during adolescence can have a lasting impact on sons' testosterone production

University of Notre Dame Associate Professor of Anthropology Lee Gettler and his collaborators have drawn on data collected over more than 30 years from almost 1,000 men in the Philippines to help shed light on the importance of adolescence and father-son experiences to sons' adult testosterone patterns.

2 Jun 2022

Researchers successfully generated Leydig cells from human iPS cells

Scientists recently succeeded in creating Leydig cells from human induced pluripotent stem (iPS) cells.

2 Dec 2021

De Novo Mutations may Play a Role in Male Infertility

In this interview, we speak to Dr. Miguel J. Xavier about his latest research into male infertility and how de novo mutations may play a part.

From Newcastle University 19 Nov 2021

Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

More informed choices of contraceptives can prevent breast cancer

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

31 May 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Study identifies new mode of male endocrine disruption due to environmental arsenic exposure

Arsenic exists ubiquitously in an organic or inorganic state in the environment. General populations are commonly exposed to arsenic by digestion.

21 Jan 2021

CRISPR technique reveals genes that regulate physiological, behavioral changes

In social hierarchy, rank is a condition that is not exclusively claimed by human beings. In the animal world, male peacocks have vividly colored plumes to show dominance, while underwater, male fish exhibit an array of vivid colors to do the same.

11 Nov 2020

New interactive tool finds toxins lurking in drinking water

Exposure to hydraulic fracturing fluid in drinking water has been shown to increase the risk of respiratory problems, premature births, congenital heart defects, and other medical problems.

24 Sep 2020

New study can help develop novel drugs for prostate cancer

The androgen receptor is considered the main driver of the growth and initiation of prostate cancer, which is known to be the second-leading cause of death in men.

15 Jul 2020

Study shows sex hormones alter the behavior of non-sex organs

In one of the first studies addressing the role of sex hormones' impact on stem cells in the gut, scientists outline new insights showing how a steroidal sex hormone, that is structurally and functionally similar to human steroid hormones, drastically alters the way intestinal stem cells behave, ultimately affecting the overarching structure and function of this critical organ.

10 Jul 2020

Loss of lipid-regulating protein drives prostate cancer metastasis

Johns Hopkins Kimmel Cancer Center researchers from the Department of Radiation Oncology and Molecular Radiation Sciences identified a lipid-regulating protein that conveys what the researchers describe as "superpowers" onto prostate cancer cells, causing them to aggressively spread.

17 Jun 2020