Transcription News and Research

RSS

Scientists determine biological mechanism that may lead to more efficient antibiotics

Hormone-mimicking molecules that trigger the production of antibiotics in soil bacteria could present new opportunities for drugs that are right under our feet.

From The University of Warwick 5 Feb 2021

LEAFY protein licenses cell reprogramming to floral fate

Cells don't express all the genes they contain all the time. The portion of our genome that encodes eye color, for example, doesn't need to be turned on in liver cells. In plants, genes encoding the structure of a flower can be turned off in cells that will form a leaf.

28 Jan 2021

Pioneer transcription factors help turn on key genes that give cells unique properties

Biologists have long wondered how complex organisms contain a variety of dramatically different types of cells with specialized functions, even though all of those cells are genetically identical.

25 Jan 2021

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

Cells need energy to survive and thrive. Generally, if oxygen is available, cells will oxidize glucose to carbon dioxide, which is very efficient, much like burning gasoline in your car. However, even in the presence of adequate oxygen, many malignant cells choose instead to ferment glucose to lactic acid, which is a much less efficient process.

20 Jan 2021

New deep neural network predicts transcription factors from protein sequences

A collaborative team of researchers have developed a deep neural network called DeepTFactor that predicts transcription factors from protein sequences.

8 Jan 2021

High-speed atomic force microscopy sheds light on structure, dynamics of intrinsically disordered proteins

Kanazawa University’s pioneering high-speed atomic force microscope technology has now shed light on the structure and dynamics of some of life’s most ubiquitous and inscrutable molecules – intrinsically disordered proteins.

29 Dec 2020

Researchers report a potential cancer drug that targets mitochondrial function

A newly developed compound starves cancer cells by attacking their "power plants" - the so-called mitochondria. The new compound prevents the genetic information within mitochondria from being read.

23 Dec 2020

Scientists find master switch that adjusts gene activity to match nutrient levels in roundworms

Transforming a fertilized egg into a fully functional adult is a complicated task. Cells must divide, move, and mature at specific times. Developmental genes control that process, turning on and off in a choreographed way.

23 Dec 2020

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

The research group led by Dr Sjoerd van Wijk from the Institute of Experimental Cancer Research in Paediatrics at Goethe University already two years ago found evidence indicating that the anti-diarrhea drug loperamide could be used to induce cell death in glioblastoma cell lines.

23 Dec 2020

Innovative gene therapy approach for regeneration of functional new neurons

Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. While decades of research have made significant progress in axonal regeneration after SCI, most of the interventions have not been translated into clinical therapies.

18 Dec 2020

Mouse stem cells converted into oocyte-like cells by just eight genes

Researchers have demonstrated that activating eight genes is enough to induce the stem cells of mice to transform into oocyte-like cells that can be fertilized.

17 Dec 2020

Researchers provide a list of genes implicated in congenital heart disease

Over two million babies, children, and adults in the United States are living with congenital heart disease--a range of birth defects affecting the heart's structure or function.

15 Dec 2020

Study elucidates genes responsible for Glioblastoma invasiveness

One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.

14 Dec 2020

New model helps assess the effect of epigenetic changes on gene expression

Researchers have developed a mathematical model to quantitatively assess the impacts of particular epigenetic changes on the transcription rates.

11 Dec 2020

Study sheds light on molecular underpinnings of long-term memory

On a late summer day in 1953, a young man who would soon be known as patient H.M. underwent experimental surgery.

From Harvard Medical School 10 Dec 2020

New method could help resolve unwanted genetic changes associated with CRISPR-Cas9 technique

A research team has used a novel method that could help resolve the issue of unnecessary genetic changes encountered in the CRISPR-Cas9 technique.

7 Dec 2020

Study sheds new light on potential risk factors for preterm birth

A recent study has detected new genetic markers linked to the duration of gestation. These findings shed new light on the possible risk factors for preterm birth.

4 Dec 2020

Scientists propose a simple model for gene regulation in higher organisms

Although the DNA and its double-helix are some of the most familiar molecules of our time, our knowledge of how cells control what genes they want to express still is rather limited. In order to create, for example, an enzyme, the information that's inscribed in our DNA about this enzyme needs to be transcribed and translated.

4 Dec 2020

Researchers identify molecular mechanisms that reverse aging

Cellular reprogramming can reverse the aging that leads to a decline in the activities and functions of mesenchymal stem/stromal cells (MSCs).

1 Dec 2020

New study refutes a major cellular process in bacteria

Despite explanations in textbooks, a new study has discovered and elucidated a cellular process that has continued to remain a mystery for researchers.

30 Nov 2020

Transcription News and Research

Scientists determine biological mechanism that may lead to more efficient antibiotics

LEAFY protein licenses cell reprogramming to floral fate

Pioneer transcription factors help turn on key genes that give cells unique properties

Study shows how nonmalignant cells adapt to harsh tumor microenvironment

New deep neural network predicts transcription factors from protein sequences

High-speed atomic force microscopy sheds light on structure, dynamics of intrinsically disordered proteins

Researchers report a potential cancer drug that targets mitochondrial function

Scientists find master switch that adjusts gene activity to match nutrient levels in roundworms

Anti-diarrhea drug could be used to induce cell death in glioblastoma cell lines

Innovative gene therapy approach for regeneration of functional new neurons

Mouse stem cells converted into oocyte-like cells by just eight genes

Researchers provide a list of genes implicated in congenital heart disease

Study elucidates genes responsible for Glioblastoma invasiveness

New model helps assess the effect of epigenetic changes on gene expression

Study sheds light on molecular underpinnings of long-term memory

New method could help resolve unwanted genetic changes associated with CRISPR-Cas9 technique

Study sheds new light on potential risk factors for preterm birth

Scientists propose a simple model for gene regulation in higher organisms

Researchers identify molecular mechanisms that reverse aging

New study refutes a major cellular process in bacteria

Expert Insights: HiMedia Labs on Advancing Nucleic Acid Extraction Across Industries

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Latest in Genomics