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Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

New View of Euchromatin in the Cell Analyzed

In their study performed, the research group discusses their novel view of euchromatin present in the cell and displays how the disclosed organization is appropriate to genome functions.

28 Jun 2023

Cell Fate Conversion Plays Crucial Role in Cancer Research

Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin and the Centre for Genomic Regulation (CRG) in Barcelona have discovered how cells speed changes to their identity known as “cell fate conversion.”

28 Jun 2023

Probiotic Bacteria may Help Maintain Brain Function in Aging Nematodes

A group from Nagoya University in Japan has discovered that when the diet of nematodes, tiny worms measuring about a millimeter or less in length, includes the bacteria Lactobacillus reuteri, the weakening of associative learning ability caused by aging does not occur.

28 Jun 2023

Analyzing the Cis-Regulatory Elements and Transcription Factors Related to Auxin Signaling

Phytohormones are chemical messengers that control the growth of plants and also their response to the environment.

27 Jun 2023

Using Pressure to Understand RNA Dynamics

Similar to how there are limitless secrets in space, there is still a lot to discover when looking at biomolecules, which are one trillion times smaller than a meter.

23 Jun 2023

New Approach to Revolutionize Synthetic Biology

For the first time, scientists at the Lawrence Berkeley National Laboratory of the Department of Energy (Berkeley Lab) have created a genome-scale method to map the regulatory role of transcription factors, proteins that are essential for controlling gene expression, and a plant’s physiological features.

22 Jun 2023

cBAF Protein Complex Controls the Fate of T Cells

The immune system protects the body from intruders, like bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs. Cytotoxic T cells are specialized immune cells that can grow into short-lived effector cells that destroy infected or malignant cells in human bodies.

14 Jun 2023

Study Sheds Light on the Genetic Basis for Body Plan Development in the Starlet Sea Anemone

Lacking bones, brains, and even a complete gut, the body plans of simple animals like sea anemones appear to have little in common with humans and their vertebrate kin.

14 Jun 2023

Exploring the Regulatory Mechanism and Physiological Significance of P62 Phosphorylation

Nuclear factor erythroid 2-related factor 2 (NRF2) is a master transcription factor with a role in maintaining oxidative stress response. It can be triggered by both redox-dependent and redox-independent pathways.

13 Jun 2023

Exploring the Tilapia Genome to Help Breed Resilient Fish

Recent research from the Earlham Institute identified candidate genes that might help fish endure warmer and saltier water, possibly providing a vital resource to drive breeding programs in freshwater aquaculture.

12 Jun 2023

Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

Computational Approach Could Uncover Transcriptional Regulatory Mechanisms and Causal Noncoding Variants

Less than two percent of the human genome codes for proteins, with the rest being noncoding and likely helping with gene regulation.

31 May 2023

Salmonella Employs Unique Tactics to Escape Cellular Defense

Salmonella enterica, a disease-causing bacterium, employs a variety of strategies to evade the human body’s defense mechanisms, much like thieves.

29 May 2023

Youth Gene "Chinmo" Could Link to Cancerous Processes

Chinmo, the gene responsible for the juvenile stage in insects, has been discovered by researchers. This gene is found in animals and could have a role in cancerous processes.

26 May 2023

Deep-Sequencing Identifies Over 10,000 Unique Genes in Cotton

TEs (transposable elements), particularly LTRs, are recognized to play a crucial role in defining basic genome organization and affecting functional gene expression. Insertion of TE or LTR fragments may also result in the formation of new transcription start sites (TSSs) in the host genome.

25 May 2023

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

St. Jude Children’s Research Hospital researchers are investigating how a type of transcription factor known as a pioneer transcription factor reaches DNA even when it is tightly wrapped.

25 May 2023

New Method can Help Identify Genome Differences Responsible for Variation in Plant Traits

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

23 May 2023

From Clocks to Cells: Unleashing the Potential of Dual Oscillatory Signaling

Christian Huygens recorded his observations of the synchronization of two pendulum clocks in 1665. It takes precise quantitative control to properly regulate oscillatory dynamics, which are seen in essential biological processes including circadian clocks, segmentation, and transcription factor responses in addition to physical systems.

22 May 2023

Research Details the Food Safety Profile of Genetically Edited Allergen-Free Eggs

Researchers have developed a chicken egg that may be safe for people with egg white allergies. Chicken egg allergies are one of the most common allergies in children.

18 May 2023