Type 2 diabetes, formerly called adult-onset or noninsulindependent diabetes, is the most common form of diabetes. People can develop type 2 diabetes at any age, even during childhood. This form of diabetes usually begins with insulin resistance, a condition in which fat, muscle, and liver cells do not use insulin properly. At first, the pancreas keeps up with the added demand by producing more insulin. In time, however, it loses the ability to secrete enough insulin in response to meals. People who are overweight and inactive are more likely to develop type 2 diabetes. Treatment includes taking diabetes medicines, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.
Obesity is a global epidemic affecting millions of people every day and is associated with comorbidities ranging from heart disease and Type 2 diabetes to osteoarthritis and social stigma.
Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.
A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation - and pointing to a surprising new ally in the fight against type 2 diabetes.
Maintaining the abundance and happiness of the good bacteria in our stomachs is a profitable endeavor supported by supplements and fad diets that promise to be the secret to gut health.
New research from the University of Sydney's Charles Perkins Centre has found that genes play an active role in shaping the bacteria found in our gut, questioning the idea that gut health is influenced only by diet.
A new study has created the first single-cell map of how DNA is regulated and organized inside different cell-types of human fat tissue.
The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.
Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early onset form of diabetes.
Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl.
Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.
This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders and uncharacterized peptides.
Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allows the body to react swiftly to stress or starvation.
Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.
Taller stature and a higher basal metabolic rate are two characteristics that distinguish modern humans from non-human primates. A genetic variant that helped these traits co-evolve was discovered by researchers and published in Cell Genomics.
A new study published in Science Advances reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes.
A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.
Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS), cardiovascular diseases and type 2 diabetes.
BRP emerges as a promising peptide for weight loss, activating appetite control pathways without triggering nausea, paving the way for safer obesity therapies.
Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).
A new study published in Communications Medicine, a Nature publication, details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people.
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