therapeutics News and Research

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Researchers Unveil Mechanisms Behind Neural Stem Cell Activation and Quiescence

A University of Ottawa neuroscientist has led a Canadian research team to reveal important new insights into the activation dynamics of neural stem cells (NSCs).

8 Feb 2025

New Gene Map Reveals Potential Drug Targets for Malaria Treatment

Researchers at Harvard T.H. Chan School of Public Health and their collaborators have created a comprehensive map of all the genes essential for blood infections in Plasmodium knowlesi, a parasite that causes malaria in humans.

7 Feb 2025

Researchers Identify Key Mechanism in Transformation of Stem Cells to Cancer Cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

Revolutionary Model Identifies Tumor-Fighting Immune Cells in Lung Cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

4 Feb 2025

New Microscopy Technique Reveals Cancer's Metabolic Secrets

Understanding how tumors alter their metabolism to evade treatments is an increasingly important area of cancer research.

4 Feb 2025

New Lipids Dramatically Improve Gene Therapy and Vaccine Delivery

Every time a shuttle docks with the International Space Station (ISS), a precise and intricate process takes place between the shuttle’s docking system and its counterpart on the station

29 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Digoxin Weakens Cancer’s Spread by Targeting Cell Clusters

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

27 Jan 2025

Study Unveils Key Genetic Mechanism Behind Antibiotic Resistance in Bacteria

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.

24 Jan 2025

Breakthrough Achieved in Completing the Creation of First Synthetic Yeast Genome

Macquarie University researchers have worked with an international team of scientists to achieve a major milestone in synthetic biology by completing the creation of the final chromosome in the world's first synthetic yeast genome.

23 Jan 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Study Reveals Key Ion Channel in Extracellular Vesicles for Cargo Transport

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their membranes intact as they negotiate shifting electrical impulses in different biological environments.

16 Jan 2025

Unrepaired DNA Damage Can Persist for Years and Lead to Cancer Mutations

While most known types of DNA damage are fixed by our cells’ in-house repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer.

15 Jan 2025

Research Shows How Sleep Clears Brain Waste

A good night's sleep does more than just help you feel rested-it might literally clear your mind. A new study published January 8 in the Cell Press journal Cell shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health.

10 Jan 2025

UK Biobank to Study Protein Changes Across 600,000 Samples

UK Biobank has today announced the launch of the world's most comprehensive study of the proteins circulating in our bodies, which will transform the study of diseases and their treatments.

10 Jan 2025

New Gene Editing Therapy Shows Promise for Treating Stargardt Disease

Researchers have developed a highly efficient gene editing therapy that could potentially treat Stargardt disease, the most common form of inherited macular degeneration.

10 Jan 2025

Researchers Discover Key Factor Behind Disease Resistance in Gene Carriers

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms.

3 Jan 2025

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024