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Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

The potential of CAR T-cell therapy for the treatment of solid tumors was unlocked in a preclinical trial by researchers at St. Jude Children’s Research Hospital who discovered a molecular mechanism. The findings were released in the journal Nature.

27 Jun 2022

Integrating Science, Software, and Data to Accelerate Antibody Discovery

As part of our SLAS Europe 2022 coverage, we speak to Andrew LeBeau, Associate Vice President for Product Integrations at Dotmatics, about the importance of managing data within the life sciences and Dotmatic's Biology Solution for Antibody Discovery.

From Dotmatics 16 Jun 2022

Novel nanoparticle therapeutic shows potential for treating human cancers

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

15 Jun 2022

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Orbit Discovery Ltd., (“Orbit”) a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, has been awarded a Smart grant by Innovate UK, the UK’s innovation agency.

From Orbit Discovery 14 Jun 2022

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

The three types of rotavirus that cause gastroenteritis in individuals, known as groups A, B, and C, are the most well-known and afflict predominantly youngsters.

10 Jun 2022

New chemical-only process may represent an important breakthrough in creating customized mRNA vaccines

At the Nagoya University in Japan, scientists have come up with a new chemical-only process that might signify an essential discovery in making tailored mRNA vaccines for a range of diseases and enable the low-cost making of mRNA in large quantities.

9 Jun 2022

Study identifies the regulatory function of non-coding 7S RNA

In human cells, a non-coding RNA molecule controls mitochondrial gene expression, according to new research published in the journal Cell. The research is the result of a collaboration between Sweden’s University of Gothenburg and Karolinska Institutet, as well as Germany’s University of Cologne.

3 Jun 2022

Sharks may be key to developing effective COVID-19 treatments

To combat viruses, one of humankind's oldest threats, researchers are studying predators with the oldest adaptive immune system in the animal kingdom: sharks.

1 Jun 2022

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Proteins are made in cells in the same way as they are made in factories. However, making too much at the wrong moment may lead to illnesses like cancer, so they use RNA interference (RNAi) to regulate production.

1 Jun 2022

Researchers determine intracellular antibodies to cure diseases

Mermaid Bio GmbH of Munich, Germany, and WEHI of Melbourne, Australia, recently announced cooperation to identify and develop a unique class of therapeutic candidates that modify misbehaving proteins inside cells that can cause a variety of diseases.

1 Jun 2022

Researchers analyze the involvement of immune cells in lung cancer survival

Lung cancer affects approximately 48,500 persons in the United Kingdom every year. New treatments are urgently needed because only around 20% of patients live 5 years after diagnosis, and it is the leading cause of cancer death.

1 Jun 2022

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Researchers at Tel Aviv University, led by Prof. Illana Gozes from the Department of Human Molecular Genetics and Biochemistry at the Sackler Faculty of Medicine and the Sagol School of Neuroscience, have unraveled a mechanism shared by mutations in the genes ADNP and SHANK3, which cause autism, schizophrenia, and other conditions.

25 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

24 May 2022

therapeutics News and Research

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

Integrating Science, Software, and Data to Accelerate Antibody Discovery

Novel nanoparticle therapeutic shows potential for treating human cancers

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Orbit Discovery awarded Innovate UK grant to expand high throughput cell-based functional screening platform capabilities in peptide drug discovery

Researchers utilize AI to reveal hitherto unknown 3D structures in rotavirus spike protein

New chemical-only process may represent an important breakthrough in creating customized mRNA vaccines

Study identifies the regulatory function of non-coding 7S RNA

Sharks may be key to developing effective COVID-19 treatments

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Researchers determine intracellular antibodies to cure diseases

Researchers analyze the involvement of immune cells in lung cancer survival

A novel mechanism shared by mutations in varied genes could help treat neurological diseases

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

Researchers devise a new treatment approach to cure aggressive brain tumors

Study shows new potential target for CAR T cells to inhibit solid tumors

New open-source tool automates RNA analysis, likely to encourage research and drug development

Study shows how nanotechnology may help for structural research of RNA molecules

RNA binding proteins in T cells help generate an effective immune response

Understanding the regulation of intramembrane proteases across the tree of life

Ben Williams

Integrating Software and Solutions to Accelerate Antibody Discovery

CHEMUK 2022: the IBioIC on Industrial Biotechnology

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