therapeutics News and Research

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PerkinElmer Completes Acquisition of Antibody and Reagent Leader BioLegend

PerkinElmer today announced it has completed its acquisition of BioLegend, a leading, worldwide provider of life science antibodies and reagents.

From PerkinElmer 22 Sep 2021

Researchers find a new way to counter immunosuppressive effect in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

21 Sep 2021

Study outlines the advantages of organoids for basic research into coronaviruses

Scientists created an organoid biobank to investigate the genes that are vital for the spreading of a SARS-CoV-2 infection.

21 Sep 2021

Study reveals how the tumor suppressor gene plays a vital role in pediatric rhabdomyosarcoma

Scientists at St. Jude Children's Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated.

20 Sep 2021

Scientists discover a new enzymatic complex that can halt cells from aging

Researchers at Université de Montréal and McGill University have discovered a new multi-enzyme complex that reprograms metabolism and overcomes “cellular senescence,” when aging cells stop dividing.

17 Sep 2021

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

New drug-based genetic platform offers a simpler, more efficient way to study gene function

Studying the role genes play on basic biology and disease is now easier, faster and more efficient, say researchers at Baylor College of Medicine.

15 Sep 2021

Scientists devise a strategy to enhance anti-tumor immunity

A synthetic molecular code exhibits the potential of enhancing the response of certain cancer patients to immunotherapy treatments.

15 Sep 2021

New technology harnesses a natural feature of therapeutic antibodies to attack blood cancer cells Researchers ...

Researchers at the University of Southampton and biopharma company UCB have found a way to enhance the natural ability of therapeutic antibodies to attack blood cancer cells using part of the human immune system known as the complement cascade, opening the way for a potential new class of treatments.

8 Sep 2021

Researchers generate first "atlas" of human melanocytes in the body

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) have generated the first "atlas" of human melanocytes located throughout the body.

3 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

Study proposes a novel approach for developing safer analgesics

Opioids are potent painkillers; however, their use is hampered as patients become tolerant to them, necessitating more and more doses.

31 Aug 2021

Study devises novel process to purify exosomes from cow’s milk

Cells produce exosomes, the nano-sized biological capsules, to protect and courier delicate molecules across the body. The capsules are hard enough to resist enzymatic breakdown and acidic and temperature fluctuations in the bloodstream and gut, which makes them a major candidate for drug delivery.

25 Aug 2021

Small synthetic molecules could one day cure or prevent COVID-19, herpes

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

Study identifies variants and genes linked to alcohol consumption

Scientists from the Icahn School of Medicine at Mount Sinai published the first of its kind research in the field of addiction genetics employing a multi-omics method to offer a huge list of causal candidate genes linked with alcohol consumption and alcohol use disorder (AUD).

24 Aug 2021

Researchers identify potent antibody that protects against a wide range of viral variants

The virus that causes COVID-19 today is not the same as the one that first sickened people way back in December 2019.

23 Aug 2021

Study discovers Parkinson’s disease-linked protein impairs mitochondria

Recently, researchers discovered that a protein linked with Parkinson’s disease can impair mitochondria.

23 Aug 2021

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

20 Aug 2021

Study reveals the biology and treatment behind rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.