Overview
A revolutionary new tool for handling 3D cellular models, spheroONE is a single, large-particle sorter and dispenser. spheroONE is the ideal platform for the selection and isolation of single spheroids, organoids, and tumoroids because it combines precision dispensing technology with sophisticated image-based sorting capabilities.
The standard 3D models will gradually take the place of conventional animal models in drug screening and other applications, which is a game-changer.
Features and benefits
Image Credit: Cellenion
- Up to 100% accurate automated isolation of single cellular aggregates using morphology and fluorescence-based sorting
- All particles from 50–600 µm in diameter
- Gentle dispensing technology maintains integrity and viability of fragile cellular aggregates (e.g., organoids)
- Biomass per well under precise control in account of user-defined number of spheroids per well and highly homogeneous populations
- Remove cellular debris to facilitate imaging and enhance drug screening results
- Compatible with any standard multiwell plate (i.e., 96, 384) in addition to custom-designed labware
- Direct visual inspection of the sample along with full image record of the isolated cellular aggregates
- By enabling the isolation and handling of cellular aggregates from 50 µm to 600 µm, including spheroids, organoids, and tumoroids, this new platform expands the single-cell dispensing solutions portfolio
- It facilitates the use of sophisticated in vitro 3D models that are more physiologically relevant, predictive, and potentially able to supplement, and in some cases even replace, animal models in drug screening and other applications, such as cancer research
- It facilitates the use of sophisticated in vitro 3D models that are more physiologically relevant, predictive, and potentially able to supplement, and in some cases even replace, animal models in drug screening and other applications, such as cancer research
- Isolate highly homogeneous spheroid populations with spheroONE
Image Credit: Cellenion
Applications
- Drug discovery
- Stem cells
- Complex in-vitro 3D models
Technology
- Technology specifically designed for dispensing: swift and gentle electromagnetic microvalve operation. Intelligent multi-parameter detection and sorting based on images
Image Credit: Cellenion
Specifications
Source: Cellenion
