Overcoming Challenges Associated with Analysis of All Pesticides

Over half of USA states have legalized use of cannabis for either recreational or medical purpose due to its therapeutic benefits for ailments such as cancer, multiple sclerosis, and others. Like any other agricultural crop, pesticides are applied to cannabis plants to protect it from pests and improve growth yield.

​​​​​​Chronic exposure to pesticides can lead to serious health risks and therefore pesticide analysis in cannabis products is important for consumer safety and quality control. Among all of states in USA, California has issued most stringent action limits for 66 pesticides residues in cannabis related matrices such as flower, cannabis infused edibles and cannabis concentrates. 

Normally pesticide analysis in cannabis and other food matrices is done by both GCMSMS and LCMSMS since some nonpolar and chlorinated pesticides such as pentachloronitrobenzene, chlordane and others are difficult to ionize with electrospray source used in LCMSMS systems. 

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