Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.
Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.
A novel tool created by researchers at Weill Cornell Medicine and the University of Adelaide has improved the capacity to monitor multiple gene mutations while concurrently recording gene activity in individual cancer cells.
In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.
MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures.
The study reviews CAR-T cell advancements in lymphoma treatment, addressing T cell exhaustion and tumor immune evasion with next-generation CAR modifications.
Researchers from Spain conducted a study on sink drains across various wards in a contemporary university hospital that follows advanced cleaning protocols.
Today, OGT announces the North American launch of its new next-generation sequencing (NGS) SureSeq™ Myeloid MRD Panel, which provides a flexible NGS workflow for the detection of ultra-low frequency measurable residual disease (MRD)-associated biomarkers in acute myeloid leukemia (AML).
A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.
In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.
The abstracts highlight the potential to improve SCD treatment using aRBCX. The first poster presents data from U.S. insurance claims, examined in a study performed with researchers at University of Pittsburgh.
Envision being a single cartwheel away from altering looks. The brown locks will turn platinum blond with just one flip. That is similar to what occurs in certain prokaryotes, or single-celled creatures like bacteria when they go through a process known as inversions.
Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.
There are approximately 100 trillion microbes in the human gut on average, and many of them are always vying for scarce resources.
Researchers at the Josep Carreras Leukaemia Research Institute have identified the genetic foundation for newborn B-cell Acute Lymphoblastic Leukaemia (B-ALL) glucocorticoid resistance through MLL gene rearrangements.
CARISMa scientists at Goethe University Frankfurt introduced innovative CAR therapy that recognizes and specifically kills tumor cells. This cancer therapy is the focus of new federally funded LOEWE research.
The most recent results from a clinical trial were given by researchers in an effort to find a cure for sickle cell disease, a painful genetic blood illness that has few available treatments.
Immune checkpoint inhibitors (ICIs), widely employed anticancer agents, have been found to impact bone turnover, potentially conferring a protective effect on bone through the promotion of osteogenesis.
Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.
Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.
Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.
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