Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.
Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.
Antonie van Leeuwenhoek stated that a single-celled eukaryote (Vorticella) and its appealing ultrafast cell contraction was the first set of discoveries. This was told in his famous letter to the Royal Society dated October 9th, 1676.
Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.
Researchers from the University of Galway have reported a new discovery that could enhance treatment options for superbug MRSA infections using penicillin-type antibiotics that have proven ineffective on their own.
Numerous sites in the brain where RNA is altered over the course of a person’s lifespan through a process known as adenosine-to-inosine (A-to-I) editing have been identified by Mount Sinai researchers.
A research team led by the Technical University of Munich (TUM) has succeeded for the first time in producing a molecular electric motor using the DNA origami method.
Numerous cells, including neurons, depend on the intracellular messenger molecule cyclic adenosine monophosphate (cAMP) to function. It does this by encouraging axon growth and maintaining neuronal communication.
Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.
The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.
Researchers from Germany’s Max Planck Institute for Plant Breeding Research (MPIPZ) and the University of Cologne have identified a new biochemical process that explains how immune proteins protect plants against invading microbes. Their results have been reported in Cell.
Researchers aim to learn more about circadian rhythms, which are the 24-hour internal clock cycles of sleeping and waking that happens in all species, including humans, plants, fungi, and bacteria.
Biological functions rely on accurate cellular communication involving different molecules. Most major signaling pathways involved in such communication, called signal transduction, often involve a family of kinases—enzymes catalyzing the transfer of phosphates between specific substrate molecules.
Every kind of T cell has a job to do. A healthy immune system makes sure no T cell oversteps.
Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.
The microbes that live inside our mouths, collectively known as the oral microbiome, impact our overall health in many ways that are not yet fully understood.
Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.
Scientists recently discovered metabolites in the human microbiome that hinders COVID-19 infection in cell-based models of the virus.
Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.
Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.
Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.