Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Study offers novel therapeutic opportunities to prevent breast tumor recurrence

Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.

28 Oct 2021

New biomarker can help characterize specific types of asthma and COPD

Rutgers researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways.

21 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Worm cells sense metabolism changes to stimulate their defense against pathogens

Microbial infections form part of the wider repercussions of the COVID-19 pandemic, and researchers are focusing more on such infections.

1 Jun 2021

Routine cleaning and sanitation are key to prevent microbial contamination in food products

Spoilage and foodborne illness could be reduced by using specially designed rapid-testing ATP swabs to clean surfaces in commercial food processing facilities.

7 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

Synthetic cannabinoid reduces essential tremors by activating astrocytes

A research team from the Department of Neuroscience at the Faculty of Health and Medical Sciences has now made a recent finding that may prove crucial to upcoming studies and treatments using medical cannabis.

19 Mar 2021

RNA-editing events can reveal the genetic basis of many human diseases

Scientists from CHOP have detected RNA-editing events that affect the expression of genes and the phenotypic manifestation of that specific expression.

10 Mar 2021

New sensor can rapidly detect RNA and DNA molecules

According to a new study, a tiny sensor used in brain chemistry research can rapidly identify the crucial molecules that offer the genetic instructions for life.

5 Mar 2021

New report highlights coffee's effect on sleep

The Institute for Scientific Information on Coffee (ISIC) published a new report today, titled 'Coffee and sleep in everyday lives', authored by Professor Renata Riha, from the Department of Sleep Medicine at the University of Edinburgh.

5 Feb 2021

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Study shows why obese mothers tend to have children susceptible to metabolic diseases

A Brazilian study published in the journal Molecular Human Reproduction helps understand why obese mothers tend to have children with a propensity to develop the metabolic disease during their lifetime, as suggested by previous research.

27 Jan 2021

Caffeinated coffee helps to minimize reductions in attention and cognitive function

A new study exploring the impact of repeated sleep loss during a simulated working week has found that consuming caffeinated coffee during the day helps to minimize reductions in attention and cognitive function, compared to decaffeinated coffee.

22 Jan 2021

Twist‐and‐squeeze mechanism of transporter protein confers cancer drug resistance

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences, discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years.

29 Dec 2020

Chromosomal instability is associated with cancer's aggressiveness

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether.

29 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Experimental vaccine shows promise for treating and preventing cancer in mice

An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice.

23 Oct 2020

New nanoparticles can destroy drug-resistant cancer cells

Multidrug resistance, or MDR, is a process in which tumors become impervious to numerous drugs and is a major cause of failure in cancer chemotherapy.

19 Oct 2020

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

It's one of the world's deadliest animals, and it has a taste for human blood: the mosquito. Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020