Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Multiple changes in brain cells during the first month of embryonic development may contribute to schizophrenia later in life, according to a new study by Weill Cornell Medicine investigators.

17 Dec 2021

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

For the first time, scientists have identified a rare population of potentially toxic senescent cells in human brains that can serve as a target for a new Alzheimer's disease treatment.

13 Dec 2021

First molecular structure of TDP-43 could pave the way for new ALS therapies

Scientists have determined for the first time the structure of the molecule associated with amyotrophic lateral sclerosis (ALS) and multiple other neurodegenerative diseases.

9 Dec 2021

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

New research from the University of Chicago points to microglia, key immune cells in the brain, as a key mediator in the relationship between the gut microbiome and b-amyloid deposits in male mice in a model of Alzheimer's disease.

3 Dec 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

When immune cells move throughout the brain, they act as the first line of defense against viruses, toxic materials and damaged neurons, rushing over to clear out them.

8 Nov 2021

Multiple sclerosis drug improves memory in mouse model of Alzheimer's disease

Losing memory is a hallmark of Alzheimer's, a symptom of the disease that depletes a patient's quality of life. Improving memory and slowing cognitive changes caused by the disease is an ongoing challenge for researchers seeking to develop novel therapies.

8 Nov 2021

New insight into how neurons and astrocytes work together to form healthy synapses

Brain cells called astrocytes play a key role in helping neurons develop and function properly, but there's still a lot scientists don't understand about how astrocytes perform these important jobs.

26 Oct 2021

Novel research reveals a vital but previously unknown role for microglia

University of Virginia School of Medicine researchers have revealed a vital but previously unknown role for immune cells that protect the brain from disease and injury: The cells, known as microglia, also help regulate blood flow and maintain the brain's critical blood vessels.

18 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

12 Oct 2021

Common drug to treat cancer reverses Alzheimer’s symptoms in mice

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.

6 Oct 2021

Genome Research' special issue covers advanced developments in single-cell genomics

Genome Research (https://genome.org) publishes a special issue highlighting novel advances and insights in Single-cell Genomics.

5 Oct 2021

Researchers identify host entry factor for Rift Valley fever virus

Rift Valley fever virus causes economically devastating outbreaks of hemorrhagic fever in livestock such as sheep, goats and cattle. These mosquito-borne outbreaks lead to infection in people working with dead or dying animals, sometimes causing hundreds of human cases and dozens of deaths.

24 Sep 2021

Alzheimer's Disease News and Research

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

First molecular structure of TDP-43 could pave the way for new ALS therapies

Immune cells in the brain mediate the link between gut microbiome and amyloid beta deposits

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Researchers investigate how brain's immune cells relate to a gene mutation in Alzheimer's disease

Multiple sclerosis drug improves memory in mouse model of Alzheimer's disease

New insight into how neurons and astrocytes work together to form healthy synapses

Novel research reveals a vital but previously unknown role for microglia

Researchers map proteo-genomic connections between different human diseases

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

Common drug to treat cancer reverses Alzheimer’s symptoms in mice

Genome Research' special issue covers advanced developments in single-cell genomics

Researchers identify host entry factor for Rift Valley fever virus

Study explores the benefits of the MIND diet for older adults

Study uses mouse models to identify the likely cause of Alzheimer's disease

Researchers develop novel cell reprogramming strategy to slow down glioblastomas

Scientists use stem cells to investigate the genetic risk for Alzheimer's disease

NYU Tandon professors show broad therapeutic potential of novel peptide to combat multiple diseases

Paving the Way for a New Lab-Grown Meat

Using E.Coli to bring 3D Printing to Life

Fluidlab; Combining Cell Counting and Spectrometry to Improve Fluid Analysis

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