Bone News and Research

RSS

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence cell survival, proliferation, and differentiation.

6 Jun 2024

Immune Checkpoint Inhibitors Confer a Protective Effect on Bone by Promoting Osteogenesis

Immune checkpoint inhibitors (ICIs), widely employed anticancer agents, have been found to impact bone turnover, potentially conferring a protective effect on bone through the promotion of osteogenesis.

3 Jun 2024

Protein Imbalance Linked to Rare Developmental Disorder

According to a recent study from the University of Lausanne, serious intellectual impairments can result from both an excess or a shortage of a single protein.

31 May 2024

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Whether loading vincristine sulfate into mesenchymal stem cell-derived exosomes could improve the targeted delivery of the drug specifically to cancer stem cells.

21 May 2024

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

16 May 2024

LSTM Scientists Discover Treatment for Tissue Damage by African Spitting Cobra Venom

Scientists at Liverpool School of Tropical Medicine (LSTM) have discovered a groundbreaking new snakebite treatment to prevent the devastating tissue damage caused by African spitting cobra venom.

11 May 2024

Leveraging the Materiobiology Approach to Design Biomaterials for Aged Bone Repair

In the elderly, a multitude of factors contribute to diminished bone regeneration capabilities, including a reduction in the self-renewal and differentiation abilities of mesenchymal stem cells, an excessive accumulation of inflammatory signals, compromised blood vessel regeneration capacity, an imbalance between bone anabolism and catabolism, and inadequate bone innervation.

13 Apr 2024

Different Chromosomes Found to Have Separate End-Specific Telomere-Length Distributions

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Research Sheds Light on Blood Cell Production in Mouse Skeleton

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

25 Mar 2024

Reducing Iron May Reverse Stem Cell Aging

It is fascinating to learn how researchers at the Albert Einstein College of Medicine and the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have discovered a way to prevent or even reverse the function of hematopoietic (blood-forming) stem cells (HSCs) as they age.

11 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

UMass Amherst Study Shows Promise in Retraining Immune Cells for Targeting Aplastic Anemia

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

28 Feb 2024

Researchers Unveil New Mechanism of Immune Cell Training in Thymus Gland

Immune cells must learn not to attack the body itself. A team of researchers from the Technical University of Munich (TUM) and the Ludwig Maximilian University of Munich (LMU) has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the "training" of the T cells in the thymus gland.

22 Feb 2024

Bone News and Research

Critical NPC Protein Nup358 Linked to Myeloid Disorders

Immune Checkpoint Inhibitors Confer a Protective Effect on Bone by Promoting Osteogenesis

Protein Imbalance Linked to Rare Developmental Disorder

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Herpes Gene Therapy Achieves 90% Viral Reduction in Pre-Clinical Studies

LSTM Scientists Discover Treatment for Tissue Damage by African Spitting Cobra Venom

Leveraging the Materiobiology Approach to Design Biomaterials for Aged Bone Repair

Different Chromosomes Found to Have Separate End-Specific Telomere-Length Distributions

Research Sheds Light on Blood Cell Production in Mouse Skeleton

Reducing Iron May Reverse Stem Cell Aging

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

UMass Amherst Study Shows Promise in Retraining Immune Cells for Targeting Aplastic Anemia

Researchers Unveil New Mechanism of Immune Cell Training in Thymus Gland

Ancient DNA Study Finds Evidence of Chromosomal Disorders

Mayo Clinic Researchers Analyze Zombie Cells to Explain Aging

CAR Peptide Accelerates Tissue Repair and Minimizes Scarring

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Understanding How Inherited DNA Variations Influence Blood Cancer Development

A Pair of Force-Activated Gene Regulating Proteins Guide Fetal Bone Development

ADSC-Exos and BMSC-Exos Protect Retinal Ganglion Cells From Hydrostatic Pressure Damage

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics