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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Researchers use CRISPR gene editing tool to analyze globin gene switching

CRISPR gene editing—a form of “molecular scissors”—was used by UNSW researchers to investigate how deletions in one section of the genome might impact the expression of surrounding genes.

From The University of New South Wales (UNSW) 19 Apr 2022

A new breakthrough in the quest to improve photosynthesis in certain crops

A Cornell University study describes a breakthrough in the quest to improve photosynthesis in certain crops, a step toward adapting plants to rapid climate changes and increasing yields to feed a projected 9 billion people by 2050.

19 Apr 2022

Powerhouse-pruning protein may be a sound target to help trigger new blood vessel growth

A protein that helps keep our cell powerhouses working at a premium appears to also help make energy rapidly available when it's time to make new blood vessels.

5 Apr 2022

Researchers employ CRISPR gene-editing technology in human blood to cure HIV

Northwestern Medicine researchers are employing recent developments in CRISPR gene-editing technology to discover novel biological method that could lead to longer-lasting treatments and new therapeutic tactics for the Human Immunodeficiency Virus (HIV).

5 Apr 2022

Evonetix granted patent for technology enabling thermally-controlled DNA synthesis

EVONETIX LTD (‘Evonetix’), the synthetic biology company bringing semiconductor technology to DNA synthesis, today announced it has been granted patent EP3551331B1 in Europe for its proprietary thermal control technology for DNA synthesis, as well as the design and manufacture of its silicon chips.

From Evonetix 4 Apr 2022

Researchers determine major protein complexes that cause ribosome production

Scientists at UT Southwestern have discovered a four-protein complex that seems to play a significant function in the formation of ribosomes, which serve as protein factories for cells, as well as a surprise role in neurodevelopmental diseases.

1 Apr 2022

Study shows how CRISPR RNAs help the immune system to identify and combat viruses

What tasks must be completed today, and which are the most vital? In their daily lives, people must continuously make priorities. Bacteria are no exception: while using CRISPR to battle viruses, they must prioritize as well. However, the method by which this priority is accomplished is unknown.

23 Mar 2022

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Researchers have created a novel method that allows them to correlate particular genes to complex tumor properties at a size and resolution that has never been achievable.

21 Mar 2022

A fresh perspective on genome-editing tools, likely to help microbial communities

Microbial communities in nature are made up of a variety of bacterium species. This makes it challenging to isolate and culture individual bacterium species in the laboratory. New tools have been created by researchers to assist.

21 Mar 2022

Scientists use mRNA delivery to enhance muscle power

Mutations that cause muscle atrophy can be corrected using the CRISPR-Cas9 gene-editing tool.

16 Mar 2022

Yale researchers find a way to 'supercharge' tumor-attacking T cells

Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat.

11 Mar 2022

Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

New technique controls gene activity without altering the DNA sequence of the genome

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical "off switches" that silence them.

7 Mar 2022

Researchers redevelop Cas9 that is unlikely to cut the wrong DNA

At times, the molecular machinery makes alterations to the wrong part of a host’s genome, generating the likelihood of an effort to repair a genetic mutation.

4 Mar 2022

Attacking a protein in prostate cancer cells stops the disease spread, research finds

Cedars-Sinai scientists discovered that attacking a protein present in prostate cancer cells could stop the disease from further spreading to various other parts of the body.

2 Mar 2022

Researchers discover a new epigenetic mark in small freshwater animals

Your DNA holds the blueprint to build your body, but it's a living document: Adjustments to the design can be made by epigenetic marks.

1 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

TGen collaborates with Deepcell to employ AI for analyzing single cell morphology

The Translational Genomics Research Institute, an affiliate of City of Hope, is partnering with a Silicon Valley firm to become one of the first research institutes in the world to employ a new Artificial Intelligence-powered imaging and sorting technology to classify and isolate individual diseased cells.

23 Feb 2022

Novel tool for genome-wide design, evaluation of gRNA sequences for CRISPR experiments

Commercially viable biofuel crops are vital to reducing greenhouse gas emissions, and a new tool developed by the Center for Advanced Bioenergy and Bioproducts Innovation should accelerate their development -; as well as genetic editing advances overall.

18 Feb 2022

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field.

17 Feb 2022