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New Therapeutic Devices for Diseases with ‘Internet of Life’

Although an electronic gadget and E. coli bacteria might not seem to have much in common, University of Maryland researchers recently connected them to create the first closed-loop system capable of communication across the technological and biological divide.

6 Mar 2024

CSHL Researchers Unravel Why Some Splicing-Based Drugs Tend to Work Better Than Others

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing.

6 Mar 2024

'lncREST' RNA Unveiled as Key Player in DNA Replication Stress Response

Researchers at Cima Universidad de Navarra have discovered that a ribonucleic acid that does not contain information to make proteins (long non-coding RNA) plays a crucial role in signalling and repairing errors in DNA replication during cell division.

5 Mar 2024

Protein RAD51 Acts as Guardian Against DNA Over-Replication

Every time a cell divides, its DNA is duplicated so that the two daughter cells have the same genetic material as their parent.

5 Mar 2024

Researchers Identify Proteins to Reprogram Fibroblasts into Limb Progenitor Cells

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

5 Mar 2024

3D Visualizations of the Copying Machinery Found in Chloroplasts

Plants have to carry out photosynthesis and ultimately synthesize oxygen and chemical energy with the assistance of sunlight to support life on Earth.

4 Mar 2024

Paleogenomics Unveils the Evolutionary Journey of Modern Humans

Writing a commentary in the 50th anniversary issue of Cell, FU Qiaomei and E. Andrew Bennett, both of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, explored the contribution of paleogenomics to our understanding of the evolution of modern humans.

1 Mar 2024

Researchers Unveil a Key Gene with a Central Role in Learning and Memory Across Mammalian Brain Cells

Discoveries in mice could guide the quest for treatments aimed at addressing brain developmental disorders in children with SYNGAP1 gene mutations.

1 Mar 2024

Researchers Create Groundbreaking RNA and DNA Solutions to Shield Plants from Viral Attacks

Customized RNA or DNA molecules have been shown to effectively combat viral infections in plants, as demonstrated in a recent study conducted by Martin Luther University Halle-Wittenberg (MLU) and published in the International Journal of Molecular Sciences.

1 Mar 2024

Astrocyte-Rich Brain Organoid Model Unveils Insights into Neuroinflammation

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

1 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

Neuroscientists Uncover Significance of Glial Cells in Brain Communication

Neuroscientists at Fred Hutchinson Cancer Center have found that an often-overlooked type of brain cell called glia has more of a role in brain function than previously thought.

29 Feb 2024

Study Reveals Genetic Mechanism Behind Human Tail Loss

A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys, finds a new study led by researchers at NYU Grossman School of Medicine.

29 Feb 2024

New "Tissue-in-a-CUBE" Offers Alternative to Animal Testing in Drug Development

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

29 Feb 2024

Exploring Gene Behavior Patterns With Cutting-Edge Technology

In an effort to comprehend how the genetic makeup and environment interact to cause diseases, scientists have studied the structure, sequencing, and interactions of genetic material with proteins in great detail.

29 Feb 2024

Study unveils how our cells outsmart invaders without turning against us

The human immune system is a sophisticated network of cells and proteins created to defend against dangerous infections, and cells continuously repel invaders in a microscopic war raging inside human bodies.

29 Feb 2024

Genetic Mechanisms of Alzheimer's Revealed in Colombian Kindred

UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer's disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.

28 Feb 2024

How Agriculture Shaped Malaria Resistance in Ancient Eastern Arabia

According to a recent study, people in ancient Eastern Arabia seem to have been resistant to malaria once agriculture arrived in the area about 5,000 years ago.

28 Feb 2024

Cyanobacteria as a Key Ingredient in Sustainable Protein-Rich Foods

We all know that we ought to eat less meat and cheese and dig into more plant-based foods. But whilst perusing the supermarket cold display and having to choose between animal-based foods and more climate-friendly alternative proteins, our voices of reason don't always win.

28 Feb 2024

The Role of RNA Modifications in Stress Granule Dynamics

An intriguing finding regarding how human cells protect themselves under stressful conditions has been revealed in a recent study conducted by an international research team. According to the research, a little genetic alteration known as ac4C serves as an essential defender by assisting cells in producing stress granules, which are units of defense.

28 Feb 2024