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Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.

21 Mar 2022

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

According to plant scientists at RIKEN, a class of non-steroidal anti-inflammatory drugs might be useful for studying the molecular processes underlying plant immunity.

21 Mar 2022

Study shows that mechanical stress help cancer cells metastasize

A recent study shows that compressing cancer cells through tight spaces makes them more violent and helps them avoid cell death.

9 Mar 2022

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

1 Mar 2022

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Drug resistance is a major obstacle in the treatment of cancers. In an aggressive type of pancreatic cancer, for instance, drug resistance is associated with the suppression of programmed cell death, which results in the uncontrolled growth of cancer cells.

25 Feb 2022

Researchers analyze how RNA molecules control the repair of damaged DNA in cancer cells

A new study from Sweden’s Karolinska Institute demonstrates how some RNA molecules regulate the repair of damaged DNA in cancer cells.

25 Feb 2022

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

An international team led by the Case Western Reserve University School of Medicine has discovered novel properties of the protein Gasdermin B that promotes repair of cells lining the gastrointestinal tract in people with chronic inflammatory disorders like Crohn's disease and ulcerative colitis.

8 Feb 2022

Study reveals how the body controls inflammation during removal of damaged cells

A research team from Cologne and Osnabrück has investigated in detail how messenger substances signal inflammation during the removal of damaged cells in the body.

7 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Researchers analyze motor protein movement in neurons

A thread-like highway, called microtubule tracks, allows motor proteins to transport cargo inside neurons.

21 Jan 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Moffitt researchers unravel the role of B cells in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022

Researchers identify molecules responsible for dangerous neutrophil behavior

Researchers have found that circulating neutrophils—a kind of immune cell—acquire distinct behavior patterns during inflammatory processes.

7 Jan 2022

Simple, marine-dwelling creature shines light on cancer resistance

A simple, marine-dwelling creature known as Trichoplax adhaerens has some remarkable properties. The organism can tolerate unusually high doses of radiation that would kill most other forms of life. T. adhaerens has another intriguing characteristic: the ability to resist cancer.

24 Dec 2021

Cell Death News and Research

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Non-steroidal anti-inflammatory drugs help to enhance crop genome editing tools, study says

Study shows that mechanical stress help cancer cells metastasize

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Microbes hindering cancer therapy seem to play a bigger role than helpful ones

Scientists elucidate mechanism that causes treatment resistance in aggressive pancreatic cancer

Researchers analyze how RNA molecules control the repair of damaged DNA in cancer cells

Groundbreaking discovery could lead to the design of novel therapeutics for wound-healing

Study reveals how the body controls inflammation during removal of damaged cells

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Researchers analyze motor protein movement in neurons

New finding could lead to the development of cell death regulators for cancer therapies

Moffitt researchers unravel the role of B cells in endometrial cancer

Pyroptosis is not a one-way ticket, it can be halted and controlled

Researchers identify molecules responsible for dangerous neutrophil behavior

Simple, marine-dwelling creature shines light on cancer resistance

COVID-19 virus spreads through cell-to-cell transmission

Researchers uncover a new signaling pathway essential for T cell viability

Study identifies novel function for existing protein

Study uncovers mechanism that triggers cancer cell death

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