Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy products. Too much cholesterol in the blood may build up in blood vessel walls, block blood flow to tissues and organs, and increase the risk of developing heart disease and stroke.
A recent genetic finding supports the theory that abnormal lipid (fat) transport pathways inside brain cells cause motor neuron degenerative disorders.
Researchers have completed the sequencing and characterization of the oat genome.
Researchers at UT Southwestern have uncovered a molecular path that allows cells to detect when their lipid supplies are running low, triggering a flurry of activity that avoids starvation.
Polygenic risk scores (PRS) are promising tools for forecasting disease risk, but current versions have bias built-in, which can reduce their accuracy in some populations and lead to health disparities.
The in-built mechanism of recycling dead or poisonous material to preserve the health of human cells is critical to general health.
According to the Alzheimer’s Association, around 11% of the population, comprising 65-year old and above—in the United States has been diagnosed with Alzheimer’s disease (AD), the most prevalent form of dementia that causes memory loss and cognitive impairment.
A risk score based on a gene map predicted the likelihood of high blood pressure leading to heart problems or stroke in people with Type 2 diabetes, according to a study published today in the American Heart Association's peer-reviewed journal Hypertension.
Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.
Bacteria, fungi, and yeast are very good at excreting useful substances such as weak acids. One way in which they do this is through passive diffusion of molecules across the cell membrane. At the same time, cells need to prevent leakage of numerous small molecules.
Scientists have precisely studied the skin’s resistant barrier layer, producing the most thorough molecular map of its form to aid in the creation of novel skin products and treatments.
A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD)-; and found that users at high risk sought out appropriate medication after using the app.
New research may help scientists locate immature cells in the central nervous system that could shed light on the causes of neurodegenerative diseases like multiple sclerosis-;and autoimmune disease that affects the brain and nervous system-;and allow for the development of better therapeutic treatments.
According to a new study, simultaneous measurement of dozens of types of fats in the blood known as “lipidomics”, can predict the risk of type 2 diabetes.
An interdisciplinary research team at The University of Texas at San Antonio has successfully developed an innovative inhibitor that shows promise in fighting obesity and potentially preventing heart disease.
Dignity Health in Arizona is introducing the first research study in North America that will use genetic testing to pinpoint men and women who are at risk of developing a cardiovascular disease based on the composition of their DNA.
Recent research identified the major genes involved in coronary heart disease and cardiac arrest.
In this interview, we speak to Dr. Santiago Miriuka, CEO of MultiplAI Health, about the importance of having diverse genomics data in research.
In this interview, we speak to Dr. Matthew Baker about his latest research that led to the programming of DNA 'robots' that are able to prod cell membranes.
A heart attack or stroke can blindside people who thought they were at low risk. Now, research led by UConn Health has found a new model that could improve how we assess heart disease.
A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A.