Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid. Cholesterol also comes from eating foods taken from animals such as egg yolks, meat, and whole-milk dairy products. Too much cholesterol in the blood may build up in blood vessel walls, block blood flow to tissues and organs, and increase the risk of developing heart disease and stroke.
Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.
Alzheimer's disease (AD) continues to be one of the most difficult and common neurodegenerative diseases, impacting millions of people globally.
Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10.
Nucleus Genomics, the next-generation genetic testing and analysis company, today announced the launch of its DNA analysis product to bring the benefits of personalized medicine to everyone.
Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines
UC Santa Barbara researchers and collaborators in Colombia, Brazil and Germany are progressing toward an understanding of mechanisms that underlie Alzheimer's disease, in particular an early-onset, genetic form that has afflicted generations of an extended family in Colombia.
With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules.
Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.
When pathogens attack the body, the innate immune system goes to work protecting against the invading disease.
Worldwide, more than one billion people are obese. Obesity is a risk factor for cardiovascular disease, diabetes, and some cancers.
Paleontologists are gaining insight into life from over a billion years ago by analyzing chemical remnants in ancient rocks and studying the genetics of present-day animals.
Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.
Scientists at the University of Illinois Urbana-Champaign, in collaboration with researchers at the University of Wisconsin-Madison, have developed a novel antifungal molecule.
Previous studies studying the genomes of people with European heritage might have reported misleading results because they did not adequately account for population structure, according to a new study.
As the world grapples with unprecedented food security challenges, Flybox®, the UK’s leading agri-tech innovator, has launched its first modular end-to-end insect farm in Aylesbury, Buckinghamshire.
In living organisms, cells have a very high capacity to process and communicate information by moving molecules or ions through tiny channels that span the cell membrane. UC Santa Cruz Professor of Electrical and Computer Engineering Marco Rolandi's lab and collaborators at MIT have created a device that mimics this biological concept in order to detect disease.
Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants.
The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action.
Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.
The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.
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