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Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Scientists develop a new fluorescent label that provides a sharper image of how DNA architecture is disturbed in cancer cells.

From University of Pittsburgh 7 Mar 2022

Researchers create a regulatory map of zebrafish genome

The zebrafish is an important model organism for studying things like genetic diseases. A regulatory map of its genome has been successfully created using high-throughput experiments and AI methods, a team led by Uwe Ohler now reports in Cell Genomics and Nature Machine Intelligence.

25 Feb 2022

Recent study reveals the code involved in human gene regulation

The logic that handles gene regulation in human cells has been discovered by a team of researchers at the University of Helsinki.

24 Feb 2022

Study shows how 3D scaffolding of chromosomes is related across carnivore species

Studies comparing animal genomes generally focus on the DNA sequence itself. A new study by researchers at the University of California, Davis shows how the three-dimensional scaffolding of chromosomes is related across several species of carnivores, offering a new approach of "comparative scaffotyping" that could be used to identify related genes across species and place them in context.

From The University of California, Davis 22 Feb 2022

Study findings open new avenues for research into host-directed therapies for TB

A*STAR’s GIS and ID Labs have discovered KCNJ15, a gene linked to the human immune system’s ability to combat TB and maybe other infectious diseases.

18 Feb 2022

Study creates a new wheat mutant with resistance to disease

Chinese scientists explained their use of genome editing to produce significant disease resistance without any growth problems in a study published online in Nature.

14 Feb 2022

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

Epigenetic inheritance enhances mating in stressed out C. elegans

Sexual reproduction allows organisms to mix up their genes and develop new adaptations to survive a harsh and ever-changing environment.

8 Feb 2022

Study may pave the way for designing next generation of artificial chromosomes for data storage

Previously, researchers from Tianjin University designed and created a 254 kb digital data carrying artificial chromosome in yeast.

12 Jan 2022

Scientists discover how sponginess of stem cell nuclei controls cell differentiation

Researchers from Tokyo Metropolitan University have discovered how the sponginess and stickiness of stem cell nuclei controls how they "differentiate" into specialized cells. They found that the nucleus starts solid-like but becomes more fluid-like over time.

3 Jan 2022

Experts identify proteins that regulate dual processes

According to recent research, the protein UBR7 acts as a histone chaperone and controls histone re-deposition at certain sites at the time of DNA replication.

22 Dec 2021

Experts identify first non-coding RNA that controls chromosome loop formation

Recent research carried out by scientists from Massachusetts General Hospital (MGH) reveals that a significant player in the healthy development of female embryos also performs a vital role in controlling the behavior of chromosome loops and gene expression in both sexes.

7 Dec 2021

Chromatin News and Research

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Researchers create a regulatory map of zebrafish genome

Recent study reveals the code involved in human gene regulation

Study shows how 3D scaffolding of chromosomes is related across carnivore species

Study findings open new avenues for research into host-directed therapies for TB

Study creates a new wheat mutant with resistance to disease

Identification of a bivalent histone-mark switch essential for angiogenesis

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Epigenetic inheritance enhances mating in stressed out C. elegans

Study may pave the way for designing next generation of artificial chromosomes for data storage

Scientists discover how sponginess of stem cell nuclei controls cell differentiation

Experts identify proteins that regulate dual processes

Experts identify first non-coding RNA that controls chromosome loop formation

Live-cell probes enable visualization of the elongation phase of transcription

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Researchers use X-ray from 3rd synchrotron facility to analyze 3D structure of chromosomes

Study shows how a common gene mutation robs people of natural cancer protection

Formation of transcription factories in living cells resembles the condensation of liquids

Researchers reveal the dual function of a zinc finger protein

Study sheds light on the regulation of epigenetic modifications during the development

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