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Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

An antibody that is successfully used to treat a variety of tumors has been replaced with a tiny molecule that researchers from Tel Aviv University and the University of Lisbon have jointly found and manufactured.

9 Aug 2022

Researchers create CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells taken from the patient’s own blood are modified to contain so-called chimeric antigen receptors (CAR), which provide the T cells the ability to target and eradicate tumor cells.

8 Aug 2022

Mitochondrial DNA plays a crucial role in inflammation, study finds

Mitochondria are generally known as the powerhouse of the cell, however, growing research indicates that they may potentially be involved in inflammation.

8 Aug 2022

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

Researchers from UC, the University of Illinois Urbana-Champaign, and the University at Buffalo demonstrated that light-activated proteins can help normalize dysfunction within cells.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Even medical professionals with years of experience can spend hours researching potential illnesses in reliable medical sources (such as databases, books, and literature) to identify which diseases have phenotypic traits overlapping with the phenotypes of undiagnosed patients.

8 Aug 2022

Active immune cells provide great protection against ischemic stroke

According to research published today in the Journal of Clinical Investigation by neurologists and immunologists at the University of Pittsburgh, a special subgroup of white blood cells provides mice with quick-acting and long-lasting protection against ischemic stroke.

From University of Pittsburgh 3 Aug 2022

Genomics plays a major role in psychedelic drugs behavior

It can be crippling for those who suffer from conditions like depression, anxiety, and cluster headaches. In clinical research, psychedelic substances have demonstrated benefits as therapies for several ailments, but not in all cases.

1 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Researchers find immune-effective ways to destroy cancer cells

Treatment with chimeric antigen receptor T cells (CAR T cells) is often the last hope for patients with lymphoma, multiple myeloma, or certain kinds of leukemia.

26 Jul 2022

Research shows how protein deficiency creates motor disorders in flies

Scientists at the Universities of Bonn and Osnabrück have identified a protein that when defective in flies results in motor dysfunction.

26 Jul 2022

Researchers analyze eight assemblers on viral sequencing data

On actual viral next-generation sequencing data, a recent study compares and evaluates eight de novo genome assembly software tools.

22 Jul 2022

Study finds broadly neutralizing antibodies might help to treat or cure HIV infection

According to research, carefully formulated combinations of broadly neutralizing antibodies might effectively cure HIV while reducing the chance that the virus would evade therapy.

22 Jul 2022

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

State-of-the-art laboratories significantly expand project capacity to meet increasing market demand for Organ-on-a-Chip research services.

From CN Bio Innovations Limited 19 Jul 2022

Researchers work on DNA-delivered antibodies to stop COVID-19

A new COVID-19 antibody delivery approach has progressed to clinical trials, thanks to funding from the Defense Advanced Research Projects Agency (DARPA) and the Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND).

11 Jul 2022

New method can identify the vast number of molecules derived from food

An international team of scientists, led by researchers at University of California San Diego, report a new method called untargeted metabolomics to identify the vast number of molecules derived from food that were previously unidentified, but that appear in our blood and our stool.

From UC San Diego 11 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

Researchers get funding to develop a vaccine against ALS disease

DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.

8 Jul 2022

Study highlights retrotransposition in CRISPR gene therapy clinical trials

Worldwide clinical studies for gene therapy utilizing CRISPR/Cas9 gene editing are now underway for a number of disorders. A study from Boston Children’s Hospital that was released in Nature Communications on June 27th, 2022, alerts readers to a possible CRISPR editing risk that has not yet been identified.

8 Jul 2022

Clinical News and Research

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

Researchers create CAR T cells for cancer immunotherapy

Mitochondrial DNA plays a crucial role in inflammation, study finds

Optogenetic control of mitochondria–lysosome contacts induce mitochondrial fission with spatiotemporal accuracy

SLFN11’s surveillance part in protein homeostasis

Researchers make significant improvements to PubCaseFinder, the clinical decision support system

Active immune cells provide great protection against ischemic stroke

Genomics plays a major role in psychedelic drugs behavior

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

COVID-19 spike protein caused severe heart damage, new research shows

Researchers find immune-effective ways to destroy cancer cells

Research shows how protein deficiency creates motor disorders in flies

Researchers analyze eight assemblers on viral sequencing data

Study finds broadly neutralizing antibodies might help to treat or cure HIV infection

CN Bio opens new laboratory facilities to extend Organ-on-a-chip contract research services capabilities

Researchers work on DNA-delivered antibodies to stop COVID-19

New method can identify the vast number of molecules derived from food

Challenges in Drug Discovery; Where are we now, and where are we going?

Researchers get funding to develop a vaccine against ALS disease

Study highlights retrotransposition in CRISPR gene therapy clinical trials

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