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Scientists use new model to develop specific cancer immunotherapy

The function of the body’s immune system is to defeat diseases by detecting foreign invaders and then mounting a response against these pathogens.

28 Oct 2020

Experimental AI platform predicts best approach to cancer treatment

The U.S. Food and Drug Administration (FDA) has given final approval to only 4% of all cancer therapeutic drugs being developed.

26 Oct 2020

Metabolite of dietary soy may decrease key risk factor for dementia

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia--with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

23 Oct 2020

Novel technique could propel personalized treatments for cancer

When it comes to defeating cancer, some immune cells are mightier than others. But even the best-trained eye and today's advanced scientific tools have trouble discerning the most powerful tumor-fighting cells from the rest.

23 Oct 2020

Researchers identify a valuable source for treating pediatric cancer

For many cancers, doctors are increasingly looking to the DNA that solid tumors shed into the blood stream to help with diagnosis and monitoring.

22 Oct 2020

Researchers identify drug that could overcome tumor resistance

Scientists have discovered that a drug that may make some melanoma tumors perceptible to the immune system, enabling them to be better targeted.

15 Oct 2020

Virus-mimicking drugs may overcome immunotherapy resistance in tumors

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body's natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

15 Oct 2020

Immunotherapy using CAR NKT cells shows promise for treating solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

14 Oct 2020

Treatment using immune system T cells preserves vision of mice with retinoblastoma

A treatment that uses immune system T cells, combined with an immune-boosting drug packaged in an injectable gel, was found to preserve the vision of mice implanted with tissue from a human eye cancer known as retinoblastoma.

13 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Study shows thymoquinone compound selectively kills prostate cancer cells

According to a new study reported in the Oncogene journal, the thymoquinone (TQ) compound selectively destroys prostate cancer cells at advanced phases.

9 Oct 2020

Dried plum diet prevents bone loss associated with spinal cord injury

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

7 Oct 2020

Genetic test identifies patients with invasive lobular carcinoma at high risk of recurrence

New results to be presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.

1 Oct 2020

New precision drug targeting cancer's ability to repair DNA shows promise

A new precision drug which stops cancer from repairing its DNA has shown promise in an early-stage clinical trial - highlighting the potential of a new class of drugs known as ATR inhibitors.

29 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020