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Gut Microbiota Signatures Linked to KRAS Mutations in Colorectal Cancer Patients

For about 40% of people diagnosed with colorectal cancer (CRC), the tumor carries a mutation in a gene called KRAS. Many of those mutations have been linked to shorter survival and more aggressive forms of disease.

5 Apr 2024

Study Uncovers Genes in Gut Microbe That Play Key Role in Early Colonization After Fecal Microbe Transplant

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants,

16 Oct 2023

Key Proteins in Human Breast Milk Crucial for Baby’s Healthy Gut

The abundance of two species of bacteria known to be good for human health and used as probiotics, Clostridium butyricum and Parabacteroides distasonis, has been linked to high concentrations of key proteins in human breast milk, particularly osteopontin and κ-casein.

13 Sep 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

The “Hangry” Stage of Bacteria Cells

The word “hangry” describes individuals who become angry due to hunger. According to a recent study by Adam Rosenthal, PhD, an assistant professor in the department of microbiology and immunology, some bacteria cells experience hangry and release toxic substances into the body when they are denied certain nutrients.

5 Apr 2023

New technique uses amino acids to cure meat and poultry products

Imagine your favorite cured meat like beef jerky, pepperoni or bacon without any added sodium nitrite from any source currently necessary for color and shelf life. Wes Osburn, Ph.D., is doing exactly that.

22 Feb 2023

Microbiome therapeutic linked to quality of life improvement in patients with recurrent C. diff infection

Kevin Garey, professor of pharmacy practice and translational research at the University of Houston College of Pharmacy is reporting the first well-controlled study to demonstrate that a microbiome therapeutic, SER-109, is associated with significant quality of life improvement in patients with the debilitating recurrent infection and disease caused by Clostridium difficile (or C. diff).

1 Feb 2023

Microbiome manipulation to prevent and cure diseases

Tagbo Niepa, assistant professor of chemical engineering at the University of Pittsburgh, is inspired by this possibility in his research. His work on using the microbiome to enhance human health was recognized with a $2 million New Innovator Award from the National Institutes of Health, which funds “exceptionally creative scientists proposing high-risk, high-impact research.”

From University of Pittsburgh 5 Oct 2022

Research finds highest levels of pathogenic bacteria in urban and agricultural soils

During heavy rains, Hawaii's streams, rivers, and nearshore waters change on microscopic levels. Bacteria in these aquatic systems increase, and some of these bacteria can be harmful to human health.

8 Sep 2022

Using a novel carbon-negative route to produce commodity chemicals

Acetone and isopropanol are important chemicals for industry. They are used to produce materials from jet fuel to solvents to detergents to plastics. Currently, industry produces these two chemicals from petroleum using processes that release carbon dioxide and other greenhouse gases.

9 May 2022

Rockefeller scientists reveal how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

7 Apr 2022

Bacteria can break down waste carbon dioxide to make valuable industrial chemicals

Bacteria are known for breaking down lactose to make yogurt and sugar to make beer. Now researchers led by Northwestern University and LanzaTech have harnessed bacteria to break down waste carbon dioxide (CO2) to make valuable industrial chemicals.

22 Feb 2022

Researchers discover hydrogen-producing enzyme group that resists oxygen attack

Hydrogen-producing enzymes are beacons of hope in biohydrogen research. However, they are so vulnerable to oxygen in the air that it has not been possible to exploit their potential on a larger scale.

3 Feb 2021

Bacteriophage can play important role in microbial control

Crop plants and animals can be infected by bacterial pathogens that reduce yield, cause food wastage, and carry human pathogens that spread disease on consumption.

5 Jan 2021

Clostridium bacteria can help convert waste gas into valuable compounds

Several branches of industry discharge waste gases that contain mostly carbon dioxide and carbon monoxide.

17 Nov 2020

Study shows adverse effect of pH-dependent switch in protein interaction

Each biological process depends on pH in one way or another. The human body should maintain constant and specific pH regulation to function efficiently.

27 Oct 2020

Gut microbial development could be restored in C-section infants by fecal microbiota transplant

The human gut contains a diverse ecosystem of microbes: mainly bacteria, as well as viruses and fungi, termed the gut microbiota.

5 Oct 2020

Study: Bacterial cells from different species can combine into unique hybrid cells

Like humans, bacteria live together in communities, sometimes lending a hand -- or in the case of bacteria, a metabolite or two -- to help their neighbors thrive.

3 Sep 2020

Healthy microbiome can reduce severity of chickungunya disease

Chikungunya virus, once confined to the Eastern Hemisphere, has infected millions of people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

15 Jul 2020

Metagenomic data on intestinal microflora can open up treatments for intestinal dysbiosis

Scientists from Osaka City University, The Institute for Medical Science, and The University of Tokyo have presented intestinal viral and bacterial metagenome data from the fecal samples collected from 101 healthy Japanese persons.

13 Jul 2020