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Immune cell migration contributes to inefficient antitumor immunity, study finds

Mutations in the APC gene cause the production of intestinal polyps in persons suffering from familial adenomatous polyposis, a genetic disease that predisposes them to colon cancer.

From Institut Pasteur 15 Apr 2022

Intracellular microbiota promote cell survival during tumor progression

Bacteria promote cancer metastasis by bolstering the strength of host cells against mechanical stress in the bloodstream, promoting cell survival during tumor progression, researchers report April 7th in the journal Cell.

8 Apr 2022

New approach to assess motility and invasive capacity of cancer cells in a tissue section

There are many proteins involved in the spread of cancer. However, some of them are notably difficult to observe in patient tissue samples.

28 Mar 2022

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet.

25 Mar 2022

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Scientists develop a new fluorescent label that provides a sharper image of how DNA architecture is disturbed in cancer cells.

From University of Pittsburgh 7 Mar 2022

Researchers study how metabolomic assessment finds postmortem biomarkers indicating decedent’s diabetes mellitus history

One of the most important and difficult aspects of a forensic examination is identifying the cause of death.

2 Mar 2022

A cryptic molecule can awaken killer viruses from their slumber

Some gut bacteria have a spooky superpower: they can reanimate dormant viruses lurking within other microbes.

24 Feb 2022

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

Our immune systems have the potential to find and destroy cancer cells. But cancer cells can be clever and develop tricks to evade the immune system.

17 Feb 2022

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Joint study will assess clinical value of comprehensive genomic profiling (CGP) on cancer therapy options in patients with advanced disease

17 Feb 2022

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Cancerous tumors are made up of rapidly growing, abnormally shaped, cells that can infiltrate and destroy healthy tissues, travel to other parts of the body, and form additional tumors.

8 Feb 2022

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

8 Dec 2021

Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered.

12 Nov 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Colorectal News and Research

Immune cell migration contributes to inefficient antitumor immunity, study finds

Intracellular microbiota promote cell survival during tumor progression

New approach to assess motility and invasive capacity of cancer cells in a tissue section

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Researchers discover new fluorescent DNA label, likely to help detect cancer risk

Researchers study how metabolomic assessment finds postmortem biomarkers indicating decedent’s diabetes mellitus history

A cryptic molecule can awaken killer viruses from their slumber

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Kras oncogenes use genetic reprogramming to drive tumorigenesis

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

Genomic changes in advanced tumors reveal interactions with treatment

CRISPR screening identifies metabolic enzyme as new target for anti-inflammatory therapeutics

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Study provides insights on mucin degradation mechanisms by a group of gut bacteria

Study reports high-fat diet increases the incidence of colorectal cancer

Japanese knotweed extract could bring back cured meats on the menu of health-conscious diners

Scientists develop a new way to grow pancreatic "organoids"

Scientists develop a novel approach to analyze tumor evolution

Research reveals link between high-fat diet, gut microbiota and cardiovascular disease

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