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Developing a potential drug molecule that targets STAT5

STAT5 has generally been recognized as an enticing cancer target, but after years of research, it was downgraded to the “undruggable” category. Now, scientists at the University of Michigan Rogel Cancer Center have achieved success with a novel approach.

17 Feb 2023

How the immune response in the brain aggravates epilepsy

Biologists at the University of Iowa have conclusively connected epilepsy with the brain’s immune system.

15 Feb 2023

Pungent ginger constituent puts white blood cells on heightened alert

Ginger has a reputation for stimulating the immune system. New results from the Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM) now support this thesis.

15 Feb 2023

New family of pharmaceutical compounds that target RNA

In Jennifer Hines’ lab, a group of graduate and undergraduate chemistry students recently discovered a new family of compounds that can target RNA and interfere with its function. In the future, RNA-targeted treatments to treat cancer and metabolic diseases, together with bacterial and viral infections, could be developed using the chemical scaffold found in this research.

15 Feb 2023

Versatile molecular toolbox expands the scope of gene regulation

Rice University scientists have enlisted widely used cancer therapy systems to control gene expression in mammalian cells, a feat of synthetic biology that could change how diseases are treated.

15 Feb 2023

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Dendritic cells (DCs) are important players of the immune system with important functions such as the identification of infectious pathogens, production of cytokines (chemical signalers of the immune system), presentation of antigens to activate T-cells, and more.

13 Feb 2023

Novel compound curtails influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

10 Feb 2023

Reshuffling of gene clusters drives the evolution of sunscreen pigments in lichens

Lichens are diverse and colorful organisms that can be found in nearly every environment on Earth, from the arctic tundra to tropical rainforests.

10 Feb 2023

Researchers decipher how common environmental bacterium can digest complex waste

A common environmental bacterium, Comamonas testosteroni, could someday become nature's plastic recycling center.

7 Feb 2023

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Scientists at ISTA show that pathogens are adapting to social health care measures by ants.

3 Feb 2023

Researchers develop a sustainable two-step process to upcycle organic carbon waste

When nature designed lignin -; the fibrous, woody material that gives plants their rigid structure -; it didn't cut any corners. Incredibly slow to break down, lignin is so sturdy and long lasting that it is resistant to bacteria and rot.

1 Feb 2023

Effective new drugs to reduce the massive number of malaria cases

Malaria is known as a disastrous disease, with 247 million cases and 619,000 deaths reported in 2021 alone.

From The University of New South Wales (UNSW) 31 Jan 2023

The Journal, Artificial Intelligence in the Life Sciences, Highlights the Contributions of Women in Artificial Intelligence in the Life Sciences

The journal, Artificial Intelligence in the Life Sciences (AILSCI), published by Elsevier, is set to release a special Themed Article Collection (TAC): Women in AI in the Life Sciences.

30 Jan 2023

Newly discovered enzyme tells specific molecules precisely how to arrange themselves

Just as a choreographer's notation tells a dancer to strike a particular pose, an enzyme newly discovered by Rice University scientists is able to tell specific molecules precisely how to arrange themselves, down to the angle of single hydrogen bonds.

30 Jan 2023

Spikes protruding from red algae-derived metal-polysaccharide responsible for antimicrobial activities

Antibiotic resistant bacteria are becoming more and more of a concern as traditional sources of anti-microbial treatments become less effective.

27 Jan 2023

Valorization of industrial food processing waste to produce value added products

There is money to be made – and potential to reduce greenhouse gas emissions – by finding a second life for the potato peels, fried dough particles, cheese whey and other industrial food-processing waste products that routinely end up in landfills, according to new research.

27 Jan 2023

Study sheds new light on a lifestyle switch that occurs in marine bacteria

Scientists have detailed a lifestyle switch that occurs in marine bacteria, where they change from coexisting with algae hosts in a mutually beneficial interaction to suddenly killing them.

25 Jan 2023

How do methanogens grow on toxic sulfite?

Methanogens are microbes that produce methane when there is little or no oxygen in their surroundings.

From The Max Planck Institute 20 Jan 2023

Using fungi to transform ocean plastic waste into key pharmaceutical components

Research on fungi underway at the University of Kansas has helped transform tough-to-recycle plastic waste from the Pacific Ocean into key components for making pharmaceuticals.

18 Jan 2023

Study suggests new strategies for controlling plant biochemistry

Plant biochemists at the U.S. Department of Energy's Brookhaven National Laboratory have discovered a new level of regulation in the biochemical "machinery" that plants use to convert organic carbon derived from photosynthesis into a range of ring-shaped aromatic molecules.

12 Jan 2023

Compound News and Research

Developing a potential drug molecule that targets STAT5

How the immune response in the brain aggravates epilepsy

Pungent ginger constituent puts white blood cells on heightened alert

New family of pharmaceutical compounds that target RNA

Versatile molecular toolbox expands the scope of gene regulation

Two-step screening of aroma compounds reveals a novel and effective modulator of dendritic cells

Novel compound curtails influenza virus replication

Reshuffling of gene clusters drives the evolution of sunscreen pigments in lichens

Researchers decipher how common environmental bacterium can digest complex waste

Germs develop a sneaky way to escape the ant colony’s defense systems, study reveals

Researchers develop a sustainable two-step process to upcycle organic carbon waste

Effective new drugs to reduce the massive number of malaria cases

The Journal, Artificial Intelligence in the Life Sciences, Highlights the Contributions of Women in Artificial Intelligence in the Life Sciences

Newly discovered enzyme tells specific molecules precisely how to arrange themselves

Spikes protruding from red algae-derived metal-polysaccharide responsible for antimicrobial activities

Valorization of industrial food processing waste to produce value added products

Study sheds new light on a lifestyle switch that occurs in marine bacteria

How do methanogens grow on toxic sulfite?

Using fungi to transform ocean plastic waste into key pharmaceutical components

Study suggests new strategies for controlling plant biochemistry

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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