Cytoskeleton News and Research

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Immune cell migration contributes to inefficient antitumor immunity, study finds

Mutations in the APC gene cause the production of intestinal polyps in persons suffering from familial adenomatous polyposis, a genetic disease that predisposes them to colon cancer.

From Institut Pasteur 15 Apr 2022

Researchers find a new way to penetrate the cell using boron clusters’ superchaotropic properties

The recent research by scientists from the Centre for Research in Biological Chemistry and Molecular Materials (CiQUS, USC), together with Jacobs University (Bremen, Germany), presents a new membrane carriers’ class that leaves behind the amphiphilic paradigm.

24 Mar 2022

Study uncovers mechanisms behind rupture and repair of the nuclear envelope

The nucleus present inside the cell is surrounded by the nuclear envelope—two layers of phospholipid membrane that obstructs the nucleus from mixing with other parts of the cell—safeguarding the cell’s DNA from outside damage.

9 Dec 2021

Researchers reveal how and why cytoquakes occur

Researchers earlier identified that animal cell cytoskeletons rearrange quickly at times, starting an earthquake-like disturbance in the part of the cell.

7 Oct 2021

Researchers show how Covid-19 causes long-lasting changes in the blood cells

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: Covid-19 significantly changes the size and stiffness of red and white blood cells - sometimes over months.

30 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Researchers study the mechanical properties of prostate cancer cells treated with anti-cancer drugs

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body. The mechanical properties of prostate cancer cells treated with the most commonly used anti-cancer drugs have been investigated at the Institute of Nuclear Physics of the Polish Academy of Sciences in Cracow.

28 May 2021

Strong cell-cell junctions preserve the quiescent properties of stem cells

The skin is known to be the largest organ in the human body, and its outermost layer, called the epidermis, is renewed every three weeks.

29 Mar 2021

New statistical study shows how pairs of cancer cells interact

One of the fundamental principles of biology is the fact that cells are motile and make contact with one another.

17 Feb 2021

New insights into the biology of chytrid fungus responsible for deadly skin infection

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

9 Feb 2021

Researchers study the formation of reinforced, patterned cell walls during proto-xylem development

Trees are by far the tallest organisms on Earth. Height growth is made possible by a specialized vascular system that conducts water from the roots to the leaves with high efficiency, while simultaneously providing stability.

3 Feb 2021

Advanced methodology reveals structures of Arp2/3 complex within cells

The cells in our body are in motion. Some migrate from A to B to heal wounds or fight pathogens. They do so with the help of small "feet" at the leading edge of migrating cells, so-called lamellipodia.

22 Dec 2020

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin.

2 Dec 2020

Scientists discover new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule -- diphenylisoxazole. This molecule has been shown to be effective against human cancer cells. The research, published in the journal Bioorganic & Medicinal Chemistry Letters, makes it possible to produce an affordable cancer treatment drug.

30 Oct 2020

Type and direction of force on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

5 Oct 2020

Study shows how tumor cells gain enhanced ability to deal with crowded tumor environment

Majority of animal cells must become spherical to undergo cell division. These cells achieve this shape by rounding up and deforming their neighboring cells.

3 Sep 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

Study shows how PIM kinases enhance the motility of cancer cells

PIM kinases are essentially enzymes that support the metastatic growth and proliferation of tumor cells.

20 Aug 2020

The immune system can play a key role in improving recovery from heart attacks

International research collaboration to pioneer the field of immuno-cardiology and investigate ways to harness the power of the immune system to improve recovery from heart attacks will be led at the Perelman School of Medicine at the University of Pennsylvania by Jonathan Epstein, MD, executive vice dean, chief scientific officer and the William Wikoff Smith Professor of Cardiovascular Research.

14 Jul 2020

Simplified artificial cell sheds light on the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

26 Jun 2020