DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.
Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.
A team led by researchers at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School, Massachusetts General Hospital and the Broad Institute of MIT and Harvard has profiled in unprecedented detail thousands of individual cells sampled from patients' brain tumors.
Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.
Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.
Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.
Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh.
Researchers have created a recipe for turning skin cells into primitive muscle-like cells that can be sustained indefinitely in the laboratory.
Recent research discovered DNA signatures linked to the risk for cardiovascular disease, a breakthrough that can lead to opportunities for clinical interventions
Most of us are familiar with the fact that women live longer than men. But fellas, if we told you there was one thing that could be done to increase your lifespan, would you do it?
The largest study to date has provided a better understanding of how genes are controlled in dementia, including the identification of 84 novel genes associated with the condition.
Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.
Although all cells in an organism share the same DNA sequence, their shapes, roles, and even lifespans differ drastically.
Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.
Bisphenol F chemical (found in plastics) may cause changes in a gene that is crucial for neurological development. Researchers from the Swedish universities of Uppsala and Karlstad made this discovery.
A research team from Brazil and Portugal has identified a link between a microRNA (miRNA) and the presence of lead in an organism.
Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).
Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.
According to a recent study, sufficient rest during vacation time restored functions linked to DNA regulation in shift workers deprived of sleep.
Deep Longevity, a firm that specializes in designing artificial intelligence (AI) to monitor human aging and prolong productive longevity, has launched the first AI-powered psychological aging clocks to inspect and decode the psychosocial factors with respect to aging.
It's a fact of life that things break down. And when they do, whether it's your car, the roof, or a blocked artery, there are people who we can call to help with the repairs.