DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.
Research introduces new DNA methylation-based method for accurately assessing cell composition in the human pancreas, addressing a critical gap in diabetes research.
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 2, entitled, "Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation."
Every human cell has class I major histocompatibility complex (MHC) molecules on its surface, which are immune complexes. The immune system needs MHC class I molecules to identify and eradicate cancer.
Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.
Parents of newborns might sense a rapid aging effect during the early months of sleepless nights. Currently, researchers at the University of Leicester are exploring the intriguing possibility that the key to a long and healthy life lies in a restful night's sleep and human DNA.
A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.
Plants increasingly need to adapt quickly to preserve their existence as global warming continues to reshape ecosystems.
This study is led by Dr Cheng-Guo Duan (Center of Excellence in Molecular Plant Sciences, Chinese Academy of Sciences).
Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.
Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.
Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.
To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.
Researchers from the University of Otago have identified a crucial factor that contributes to the aggressive spread of colon cancer, marking a significant advancement in the fight against fatal tumors.
Childhood adversity-;circumstances that threaten to a child's physical or psychological well-being--has long been associated with poorer physical and mental health throughout life, such as greater risks of developing cardiac disease, cancer, or depression.
Among families with children diagnosed with autism spectrum disorder, Johns Hopkins University researchers say they have found a link between chemical "marks" on DNA in the sperm of fathers and autistic traits in their 3-year-old children.
The protein PKMzeta has been strongly associated with long-term memory formation.
New research lead by Keith Slotkin, PhD, member, Donald Danforth Plant Science Center opens the door for scientists to equip plants with the tools they need to adapt to rising levels of carbon dioxide (CO2), high heat, and other stressors associated with climate change.
A higher risk of reproductive and child health issues is linked to advanced paternal age. Increasing evidence points to age-related alterations in the sperm epigenome as one underlying cause.
Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), the Institute of Microelectronics of Barcelona (IMB-CNM-CSIC) and the Aragon Nanoscience and Materials Institute of Aragon (INMA) -;a joint institute of the CSIC and the University of Zaragoza-; have developed a new method to detect RNA viruses based on the triplex-forming probe technology.
To share nutrients and enhance their capacity for environmental adaptability, tree roots frequently collaborate with fungi. Although this interaction is mutually beneficial (namely, ectomycorrhizae), the biological mechanisms at play have not yet been completely analyzed.