DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.
A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.
The human immune system works hard to maintain an individual’s health and protect against viruses, bacteria, parasites, fungi, and cancerous cells.
The advancements in technology might come up with techniques that measure biological parameters in real-time in living organisms, which can help monitor tissue homeostasis, on the go. A significant component of such homeostasis is tissue oxygen concentration.
Without doubt, the future of life sciences is sure to have technology that can measure biological parameters real-time in living organisms.
All the cells found in the body of an individual have the same genetic code.
Crop improvement often involves the transfer of genetic material from one organism to another to produce a valuable trait. Some major examples of crops with these so-called "transgenes" include disease-resistant cotton and beta-carotene-enhanced golden rice.
Researchers from the University of Colorado School of Medicine identified specific genetic biomarkers that reveal who is infected with COVID-19.
Researchers examined tumor cells that were resistant to the original treatment and identified molecular targets for therapies that could evade breast cancer recurrence.
Mangrove trees straddle the boundary between land and ocean, in harsh environments characterized by rapidly changing levels of salinity and low oxygen.
Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.
A team led by researchers at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School, Massachusetts General Hospital and the Broad Institute of MIT and Harvard has profiled in unprecedented detail thousands of individual cells sampled from patients' brain tumors.
Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.
Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.
Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.
Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh.
Researchers have created a recipe for turning skin cells into primitive muscle-like cells that can be sustained indefinitely in the laboratory.
Recent research discovered DNA signatures linked to the risk for cardiovascular disease, a breakthrough that can lead to opportunities for clinical interventions
Most of us are familiar with the fact that women live longer than men. But fellas, if we told you there was one thing that could be done to increase your lifespan, would you do it?
The largest study to date has provided a better understanding of how genes are controlled in dementia, including the identification of 84 novel genes associated with the condition.
Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.