Drugs News and Research

RSS

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

From Harvard Medical School 23 Apr 2021

Study reveals key lipid-binding protein that contributes to cancer

Researchers have discovered how a portion of a protein communicates with a cell’s membrane to control crucial intercellular communications.

21 Apr 2021

Study shows how tau aggregates promote Alzheimer’s disease

If looked deep into the brain of a patient with Alzheimer’s disease or those suffering from the most types of dementia or the concussion-associated syndrome, called chronic traumatic encephalopathy (CTE), there would be hairball-like tangles of a protein known as tau—a common suspected culprit.

20 Apr 2021

Novel method to activate and visualize protein channels that keep bacteria alive

Almost all bacteria rely on the same emergency valves--protein channels that pop open under pressure, releasing a deluge of cell contents.

15 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Study shows that neural stem cells age quickly

A research team has revealed that neural stem cells (NSCs)—that is, the stem cells of the nervous system—age quickly.

14 Apr 2021

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

13 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

Exercise training may slow tumor growth for females with breast cancer

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have found.

13 Apr 2021

New method can improve the drug testing process

When developing a new drug, the first question is, “does it work?” and the second question is, “is it harmful?”

9 Apr 2021

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

A group of researchers from France, Germany, Belarus, Japan, and Russia and headed by a scientist from Skolkovo Institute of Science and Technology (Skoltech) has discovered how Mycobacterium tuberculosis survives in iron-deficient environments by using rubredoxin B (RubB)—a protein that belongs to the rubredoxin family and plays a significant role in adapting to varying environmental conditions.

9 Apr 2021

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

Researchers at the Francis Crick Institute have found that blocking a specific protein could increase tumor sensitivity to treatment with PARP inhibitors. Their work published in Science , suggests combining treatments could lead to improved therapy for patients with inheritable breast cancers.

9 Apr 2021

3D-printed system enables the growth of self-organizing brain tissue

A research team has created brain tissue organoids in a tiny 3D-printed system that helps them observe as they grow and develop.

7 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Genetic makeup of more than 53,000 people offers valuable insights into dangerous diseases

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death.

7 Apr 2021

Drugs News and Research

National DNA Day 2021: An Interview with Professor George Church

Study reveals key lipid-binding protein that contributes to cancer

Study shows how tau aggregates promote Alzheimer’s disease

Novel method to activate and visualize protein channels that keep bacteria alive

Novel test detects HIV reservoir in patients more accurately

Study shows that neural stem cells age quickly

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Exercise training may slow tumor growth for females with breast cancer

New method can improve the drug testing process

Study explains molecular mechanisms of drug resistance in Mycobacterium tuberculosis

Inhibiting a specific protein could increase tumor sensitivity to PARP inhibitors

3D-printed system enables the growth of self-organizing brain tissue

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Microfluidic probe sends free radicals on live cells

Genetic makeup of more than 53,000 people offers valuable insights into dangerous diseases

Researchers take a key step toward new drugs and vaccines for combating COVID-19

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

New automated process uses ultrashort peptides to print hydrogel scaffolds

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

Latest in Genomics