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Discovery on Learning and Memory Could Lead to New Alzheimer's Treatments

Scientists at the University of Colorado Anschutz Medical Campus have made a `paradigm shifting’ discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer’s disease and potentially Down syndrome.

31 Aug 2023

HydRegen Secure BBSRC, EPSRC and IUK Grant Funding to Unlock Sustainable Biocatalytic Hydrogenation

HydRegen, the biotechnology company enabling sustainable chemical manufacturing, and researchers from the University of Nottingham’s Faculty of Engineering collaborate in a project to unlock sustainable biocatalytic hydrogenation and receive grant funding from BBSRC, EPSRC and IUK to complete the feasibility study.

30 Aug 2023

T Cells Infiltrate Brain and Worsen Alzheimer's Pathology, Study Finds

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

28 Aug 2023

Study Identifies 39 Genetic Mutations Associated With Heart Failure

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

25 Aug 2023

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

A Colonizing Strategy of Salmonella Gut Bacteria

According to researchers at ETH Zurich, when the gut is already populated by a closely similar strain of Salmonella bacteria, it only requires the capacity to use a single other food source for the bacteria to flourish.

22 Aug 2023

Viral Proteins Promote the Spread of Protein Aggregates in the Brain

Viral genetic remnants found naturally in the human genome may influence the development of neurodegenerative diseases.

22 Aug 2023

Supporting Informed Decisions on Malaria Biocontrol Interventions

Following World Mosquito Day, we spoke with Dr. Michael Santos from GeneConvene Global Collaborative about using genetically engineered mosquitoes to help tackle malaria and how the Collaborative supports informed decision-making regarding this potentially game-changing technique.

21 Aug 2023

From Neanderthals to New Drugs: Unlocking Ancient Proteins

We need to think big in antibiotics research.

17 Aug 2023

New Microscope Combined with AI Software to Identify Malaria Parasites in Blood Samples

Each year, more than 200 million people fall sick with malaria and more than half a million of these infections lead to death.

11 Aug 2023

Newly Developed Antibody Therapy to Have Benefits Over Existing Opioid-Overdose Treatments

An antibody in single-chain fragment variable (scFv) format that binds to the powerful opioid carfentanil was shown to reverse signs of carfentanil overdose in preclinical tests conducted by scientists at Scripps Research.

11 Aug 2023

Deep Learning Methods Developed For Computational Protein Design

The key to understanding proteins -; such as those that govern cancer, COVID-19, and other diseases -; is quite simple. Identify their chemical structure and find which other proteins can bind to them. But there's a catch.

11 Aug 2023

Detection of Mutations in Children with Brain Tumors

Uppsala University researchers have devised a novel approach for detecting mutations in pediatric brain cancers.

8 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Reptile Conservation Could Benefit From New Range of Cell Lines

The creation of the first wide variety of reptile cell lines is highlighted in a new scientific study that was published in the journal Microorganisms.

7 Aug 2023

Determining a Network of Cellular Programs Controlling Human Cancers

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

4 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Analyzing Deep Learning Methods for Computational Protein Design

4 Aug 2023

The Peptoid Approach to Antiviral Resistance

Antiviral therapies are difficult to develop because viruses can rapidly mutate to become drug resistant.

3 Aug 2023

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023