Efficacy News and Research

RSS

Study explores the effectiveness of a natural protein against colon cancer cells

Scientists and faculty of Vanderbilt University are in search of the “Achilles’ heel” of cancer cells that survive initial chemotherapy.

From Vanderbilt University 5 Aug 2021

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord.

28 Jul 2021

New formulation to administer antibodies for choroidal neovascularization therapy

Scientists have created a new formulation based on regulatory T-cell exosomes (rEXS) to administer vascular endothelial growth factor (VEGF) antibodies.

28 Jul 2021

Cell-analysis method could pave the way for new strategies to fight tuberculosis

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.

22 Jul 2021

Study unravels the biomechanical, biophysical response of cancer cells to drugs

A new study reports the use of single-cell, force spectroscopy methods to probe biophysical and biomechanical kinetics of cancer cells.

21 Jul 2021

Atomic force spectroscopy probes cellular biomechanics in response to drugs in hypoxia

Oncotarget published "Dynamic cellular biomechanics in responses to chemotherapeutic drug in hypoxia probed by atomic force spectroscopy" which reported that by exploiting single-cell, force spectroscopy methods, the authors probed biophysical and biomechanical kinetics of brain, breast, prostate, and pancreatic cancer cells with standard chemotherapeutic drugs in normoxia and hypoxia over 12-24 hours.

20 Jul 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.

19 Jul 2021

Illinois scientists make it easier for farmers to choose plant biostimulants

Corn growers can choose from a wide array of products to make the most of their crop, but the latest could bring seaweed extract to a field near you. The marine product is just one class in a growing market of crop biostimulants marketed for corn.

16 Jul 2021

New study identifies two genetic regions linked to cluster headache

Scientists have performed the largest-ever study seeking genetic markers for cluster headache.

16 Jul 2021

Updated Families SHARE workbook helps people use family history to assess disease risk

The Families SHARE workbook was developed by researchers at the NHGRI, which is part of the National Institutes of Health (NIH).

12 Jul 2021

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Immunologists have discovered a molecular route that regulates how crucial immune cells evolve into the immune system’s functioning components.

9 Jul 2021

Universal stem cells exhibit the potential for more cost-effective cell therapy

Researchers have demonstrated that gene-edited cellular treatments can effectively treat cardiovascular and pulmonary disorders.

8 Jul 2021

Study on memory T cells of COVID-19 convalescent patients could power effective vaccine strategies

Researchers have discovered that a majority of the COVID-19 convalescent patients develop and maintain T cell memory for more than 10 months.

7 Jul 2021

Researchers uncover cellular mechanisms by which the silencing therapies act in cells

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

New method can improve the efficacy of promising treatment for recurrent glioblastoma

A promising treatment for melanoma and other types of cancers is neoadjuvant immune checkpoint blockade (ICB).

1 Jul 2021

New nanobodies could fight against SARS-CoV-2 variants

Looking for a new strategy in the long-running battle against the SARS-CoV-2 virus, researchers have developed nanobodies.

23 Jun 2021

New technique boosts the efficacy of future malaria vaccines

A new technique for obtaining pure malaria parasites from infected mosquitos could speed up the development of novel, more powerful malaria vaccinations.

21 Jun 2021