Efficacy News and Research

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Routine cleaning and sanitation are key to prevent microbial contamination in food products

Spoilage and foodborne illness could be reduced by using specially designed rapid-testing ATP swabs to clean surfaces in commercial food processing facilities.

7 May 2021

Low-dose administration of MERS DNA vaccine protects against COVID-19

The Wistar Institute has developed a synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV).

26 Apr 2021

New AI model predicts targets for previously unmapped T cells against coronavirus

A research team has created an AI technique that can bind immune cells to their targets and uncouple the types of white blood cells that identify SARS-CoV-2.

26 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

23 Apr 2021

Interferon-stimulating genes control SARS-CoV-2 replication

Researchers have found a set of human genes that combat infection due to SARS-CoV-2, the virus responsible for causing COVID-19.

20 Apr 2021

New simpler, faster system for analyzing mutations in SARS-CoV-2

Although it is known that mutations in the SARS-CoV-2 genome occurred and spread, the effect of those mutations is not yet clear.

14 Apr 2021

New stem cell therapy shows promise to help patients with non-healing diabetic foot ulcers

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

8 Apr 2021

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

A gene called KRAS is one of the most commonly mutated genes in all human cancers, and targeted drugs that inhibit the protein expressed by mutated KRAS have shown promising results in clinical trials, with potential approvals by the U.S. Food and Drug Administration anticipated later this year.

7 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Immunotherapy, which recruits the body's own immune system to attack cancer, has given many cancer patients a new avenue to treat the disease.

25 Mar 2021

Disease-driving B cells play a role in non-alcoholic fatty liver disease

A study by researchers proposes that disease-driving B cells—a kind of white blood cell—have a role in the development of non-alcoholic fatty liver disease.

23 Mar 2021

New high-throughput system for testing drug candidates to treat neurodegenerative diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

19 Mar 2021

Seaweed supplement in cattle diet effective at reducing greenhouse gases

A bit of seaweed in cattle feed could reduce methane emissions from beef cattle as much as 82 percent, according to new findings from researchers at the University of California, Davis.

18 Mar 2021

New substance could improve the treatment of drug-resistant cancers

A new substance could improve the treatment of persistent cancers. Researchers at Martin Luther University Halle-Wittenberg and the University of Greifswald have developed a new inhibitor that makes drug-resistant tumor cells respond again to chemotherapy.

9 Mar 2021

Catechin-type flavonoid compounds in tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

9 Mar 2021

Virtual clinical trials could transform the development of new drugs

New cutting-edge research undertaken at the University of Leicester could revolutionize the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials.

8 Mar 2021

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

A deep sequencing study of 747 SARS-CoV-2 virus isolates has revealed mutant peptides derived from the virus that cannot effectively bind to critical proteins on the surface of infected cells and, in turn, hamper activation of CD8+ killer T cells that recognize and destroy these infected cells.

5 Mar 2021

Three new COVID-19 variants can evade antibodies that act against original virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

Natural compound acts as reversible male contraceptive pill

Researchers have developed a novel approach that has resulted in the discovery of a natural compound that acts as a male contraceptive agent.

5 Mar 2021

Efficacy News and Research

Routine cleaning and sanitation are key to prevent microbial contamination in food products

Low-dose administration of MERS DNA vaccine protects against COVID-19

New AI model predicts targets for previously unmapped T cells against coronavirus

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Interferon-stimulating genes control SARS-CoV-2 replication

New simpler, faster system for analyzing mutations in SARS-CoV-2

New stem cell therapy shows promise to help patients with non-healing diabetic foot ulcers

Scientists discover mutations that make cancer resistant to KRAS-targeted therapies

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Disease-driving B cells play a role in non-alcoholic fatty liver disease

New high-throughput system for testing drug candidates to treat neurodegenerative diseases

Seaweed supplement in cattle diet effective at reducing greenhouse gases

New substance could improve the treatment of drug-resistant cancers

Catechin-type flavonoid compounds in tea relax blood vessels by activating ion channel proteins

Virtual clinical trials could transform the development of new drugs

Mutant peptides derived from SARS-CoV-2 hamper activation of CD8+ killer T cells

Three new COVID-19 variants can evade antibodies that act against original virus

Engineered safety switch reduces CAR-T immunotherapy-related side effects

Natural compound acts as reversible male contraceptive pill

Developing a portable tool to detect street drug ‘spice’

National DNA Day: Importance of DNA in Research

National DNA Day 2021: An Interview with Professor George Church

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