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Researchers discover effective therapy for pediatric T-acute leukemia

The most frequent type of malignancy in kids is acute lymphoblastic leukemia (ALL).

27 Jun 2022

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

In hospitals, the Staphylococcus aureus bacteria can be transported from the skin or nasal cavity into open wounds and, possibly, the bloodstream, posing a fatal hazard. Staph infections killed over 20,000 Americans in 2017, according to the Centers for Disease Control and Prevention.

20 Jun 2022

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Dietary modifications can lower symptoms of allergic reactions, a new study reveals

Micronutrient deficits can increase inflammation and make the immune system more susceptible to allergens. Iron deficiency indicates danger to immune cells and causes an excessive immunological response.

8 Jun 2022

Research shows how current drugs impact bacterial physiology

Tuberculosis is a stubborn disease caused by even more stubborn bacteria. While many bacterial infections clear up within days of taking antibiotics, TB can take up to six months to clear up and, in some cases, never leave the human body. In 2020, it claimed 1.5 million lives, second only to COVID-19 in terms of infectious disease deaths.

1 Jun 2022

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

1 Jun 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Scientists develop powerful tools using CRISPR-Cas9 to repair genetic diseases

CRISPR has marked the beginning of a new era in genomic medicine. The popular CRISPR-Cas9 has generated plenty of potent methods for curing genetic diseases.

30 May 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

New technique can reduce the incidence of leafroll disease in vineyards

Removing not only a diseased grapevine but the two vines on either side of it can reduce the incidence of leafroll disease, a long-standing bane of vineyards around the world, Cornell University researchers have found.

20 May 2022

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

A preclinical study performed by Monash University researchers discovered that utilizing a combination of phages and antibiotics to treat bacterial infections may be considerably more successful than using the drugs separately.

12 May 2022

Study explains how liver regeneration may help treat liver disease in mice

Other vertebrates, such as fish and lizards, can regenerate organs more effectively than mammals. Salk researchers have discovered a mechanism to partially restore the young condition of liver cells, allowing them to repair damaged tissue at a quicker rate than previously thought.

29 Apr 2022

Study shows the role of mucosal-associated invariant T cell in mucosal melanomas patients

Many cancer patients have benefited from the development of anti-cancer immunotherapy drugs known as immune checkpoint inhibitors, but patients with mucosal melanomas—melanomas that occur in the mucous membranes of the head, neck, eyes, respiratory system, and genitourinary region rather than on the skin—are highly resistive to immune checkpoint inhibitors for reasons researchers do not fully understand.

29 Apr 2022

Dotmatics, previously Insightful Science, set to transform the future of scientific software and data management

Dotmatics was today announced as the formal name and brand for the combined entities of Insightful Science and Dotmatics.

From Dotmatics 26 Apr 2022

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

First product within new ‘in-a-box’ range, which harnesses next-generation, human-relevant Liver-on-a-Chip technology to improve the accuracy and efficiency of NASH drug discovery.

From CN Bio Innovations Limited 26 Apr 2022

Researchers detect major contamination in organic vegetables, likely to cause fatal illness

According to a new study proposed at this year’s European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) in Lisbon, Portugal (23–26 April, 2022), disease-causing amoebas that reside on natural leafy vegetables can preserve human pathogens such as Pseudomonas, Salmonella, and Helicobacter, posing a public health hazard. Dr Yolanda Moreno and colleagues from Spain’s Universitat Politècnica de València conducted the research.

25 Apr 2022

Study underscores the crucial role of genomic profiling in diagnosing and grading brain tumors

Patients diagnosed with a type of brain tumor survived for longer when they were treated aggressively with surgery, radiation and chemotherapy.

22 Apr 2022

Rewiring the inner workings of leukemia cells to reverse drug resistance

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

20 Apr 2022