Efficacy News and Research

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Study shows metabolic state of disease-causing parasite influences its resistance to drugs

A new study has revealed how a disease-causing parasite is able to resist the present range of therapies. The study was recently published in eLife.

2 Dec 2020

New patented technique reveals the energy status of cells

Scientists have developed a novel process that may help personalize anticancer treatments.

2 Dec 2020

Research may lead to new strategies for calcium malabsorption

A Rutgers study has discovered that vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role.

From Rutgers University 2 Dec 2020

Researchers explain the effectiveness of anti-diabetic drug

An international team of researchers has explained the action mechanism of incretin-based medications in diabetes treatment.

27 Nov 2020

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

A phase 1 trial involving 12 children with relapsed neuroblastoma - a hard-to-treat pediatric cancer - shows that anticancer CAR T cells displayed signs of efficacy against these tumors while avoiding damage to nerve tissue.

26 Nov 2020

Seaweed-shaped mats can remove toxic metal ions from drinking water

A group of scientists from Osaka University has created seaweed-shaped mats made of nanofibers for use in water filters. These mats can help eliminate toxic metal ions.

From Osaka University 20 Nov 2020

High-protein total diet replacements may be a promising strategy to combat obesity

According to the World Health Organization, obesity has nearly tripled worldwide since 1975. In 2016, for example, more than 1.9 billion adults were categorized as overweight. Of these, more than 650 million had obesity.

19 Nov 2020

Researchers use new technique to visualize the world of lipid dynamics

The potential to “see” the inner mechanisms of structures provides the promise of developments in the diagnosis and treatment of various diseases.

19 Nov 2020

Several hepatitis C drugs can inhibit the SARS-CoV-2 main protease

Scientists have determined that drugs meant for treating hepatitis C can block SARS-CoV-2 main protease, which allows reproduction in the novel coronavirus.

17 Nov 2020

New study shows patients' own stem cells can be used to grow new bone

A new, groundbreaking study from the University of Bergen (UiB) shows that a patients' own stem cells can be used to grow new bone. This can potentially help millions of people who are partially edentulous and have insufficient bone for the placement of dental implants.

17 Nov 2020

Pfizer and BioNTech COVID-19 vaccine is found to be 90% effective

Pfizer and BioNTech have today announced their new vaccine candidate (BNT162b2) is 90% effective against SARS-CoV-2.

9 Nov 2020

New method to improve preclinical evaluation of CAR-T cell therapies

Ludwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-receptor (CAR) T cell therapies.

9 Nov 2020

MUSC researchers demonstrate polarized Th17 cells can effectively eradicate tumors

Adoptive transfer of T-cells can extend survival and, at times, treat patients with advanced solid tumors.

2 Nov 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Research on broadly neutralizing antibodies may lead to universal flu vaccine

New research from an immunology team at the University of Chicago may shed light on the challenges of developing a universal flu vaccine that would provide long-lasting and broad protection against influenza viruses.

23 Oct 2020

Study shows antibody levels drop rapidly in recovering COVID-19 patients

The lack of effective treatments for COVID-19 is forcing hospitals to use blood plasma from recovering patients to treat those who have severe symptoms.

19 Oct 2020

Plant genetic engineering can help address micronutrient malnutrition

More than two billion people worldwide suffer from micronutrient malnutrition due to deficiencies in minerals and vitamins.

19 Oct 2020

Researchers assess heat-stress tolerance of different varieties of sweet potato

Climate change poses a threat to the world's subsistence crops. Heatwaves, which are likely to intensify according to climate evolution predictions, are generating levels of heat stress that are damaging to agricultural production.

15 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Virologists at the KU Leuven Rega Institute have been working on two lines of SARS-CoV-2 research: searching for a vaccine to prevent infection, and testing existing drugs to see which one can reduce the amount of virus in infected people.

12 Oct 2020