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Study reveals the mechanism used by tuberculosis bacteria for their growth

The structure of a protein that plays a role in importing vitamin B12 into the cells of a tuberculosis (TB)-causing bacterium has been revealed by scientists from the Netherlands, Russia, the United States, and Sweden.

23 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

Discovery marks a critical step toward developing new anti-cancer drugs

A team of scientists led by the University of Michigan Rogel Cancer Center and Case Comprehensive Cancer Center has identified the binding site where drug compounds could activate a key braking mechanism against the runaway growth of many types of cancer.

21 Apr 2020

UTSW researchers solve structure of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction.

16 Apr 2020

New method images proteins in 3D with nanoscale resolution

A research team, which also included scientists from the National Synchrotron Light Source II (NSLS-II), has reported a novel method for imaging proteins in three dimensions (3D) with nanoscale resolution.

16 Apr 2020

New method can improve access to sophisticated microscopy data

Researchers from the University of Michigan Life Sciences Institute (LSI) have created a novel data-processing method that offers a simpler yet faster way to data produced by cryo-electron microscopy (Cryo-EM) instruments, thus making it possible to adopt this robust method at a wider scale.

16 Apr 2020

Research provides new insights into building blocks of gum disease

Porphyromonas gingivalis is a major bacterial pathogen which leads to periodontitis also known as gum disease. In Japan, 80% of adults aged 35 and over suffer from this disease. What's more, P. gingivalis has also been linked to rheumatoid arthritis, cardiovascular disease, pancreatic cancer, and even Alzheimer's disease.

15 Apr 2020

The Architecture Of A 'Shape-Shifting' Norovirus

Created from 13,000 separate images taken by an electron microscope, it reveals in rich detail the structure of the virus.

2 Apr 2020

Upgrading Biomass With Selective Surface-Modified Catalysts

Scientists have designed a catalyst composed of very low concentrations of platinum (single atoms and small clusters) on the surface of titanium dioxide.

2 Apr 2020

Ptychographic label-free microscopy platform developed for imaging

A new ptychographic label-free microscopy method has been developed to overcome the limitations of conventional optical microscopy methods.

24 Mar 2020

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

G protein-coupled receptors (GPCRs) have crucial roles to play in cell signal transduction and can be used as vital therapeutic targets for several diseases.

20 Mar 2020

Regulating ion flow using a ball-and-chain mechanism

Ion channels that permit potassium and sodium ions to move in and out of cells are essential for the function of the brain and heart, and also for neuronal “firing” in the central nervous system.

19 Mar 2020

Structure of intact IgE revealed by electron microscopy

Scientists at Aarhus University have described the structure of an IgE antibody for the very first time.

9 Mar 2020

New correlative, 3D, super resolution imaging platform reveals unexpected findings in mammalian cells

Researchers have developed a platform for the 3D super-resolution imaging at the nanoscale level that has revealed unexpected findings in mammalian cells.

21 Feb 2020