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Strategies to Counter Postnatal Growth Retardation in Piglets

The metabolic basis of postnatal growth retardation (PGR) in piglets is not yet clear, but it is characterized by poor production performance, low feed conversion rate, and a high mortality rate.

4 Mar 2024

Unlocking the Potential of Microbiome-Based Cancer Therapies

The microbiome can identify patients with rare gynecological cancers, biliary tract cancers, and melanoma who will benefit from combination immunotherapy for various cancer types.

4 Mar 2024

National Korea Maritime and Ocean University Researchers Explore the Impact of Microplastics and Toxin Exposure on Goldfish

Microplastic particles can travel long distances in oceans and are known to carry with them harmful and persistent organic pollutants like benzo[α]pyrene (BaP), a polycyclic aromatic hydrocarbon.

11 Jan 2024

Epigenetic Key Unlocks Treatment Path for Endocrine-Resistant Breast Cancer

Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

10 Jan 2024

NEUROG3 Gene Plays Key Role in Pancreas Development

Different cells in the human pancreas play important roles in blood sugar regulation. Neurogenin 3 (NEUROG3) is a gene found in pancreatic cells.

1 Sep 2023

New Findings May Provide Useful Therapeutic Approach for Treating Breast Cancer Patients

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Gut Hormone Plays a Vital Role in Maintaining the Balance of Fungi in the Digestive System of Mammals

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023

The Association Between Type 2 Diabetes Treatment Response and Genetic Variants

People who are at a high risk of developing type 2 diabetes can be prescribed a variety of medications to decrease blood sugar levels, but it is not always apparent which people would benefit from which treatments the most.

6 Jun 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

The Relation Between an Autism Gene and Infertility

The biological foundations of a reproductive disease caused by a DNA mutation have been discovered by a University of California, Riverside study. Fragile X Syndrome, a major genetic contributor to cerebral impairment and autism, is also caused by this gene mutation.

5 Apr 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

Non-nutritive sweeteners do not increase blood glucose and other endocrine responses, study shows

New research conducted by a team of scientists at the University of Toronto has shown that non-nutritive sweeteners (NNS) do not increase blood glucose and other endocrine responses.

22 Feb 2023

Pancreatic islet microexons play key role in islet function and glucose homeostasis

When cells copy DNA to produce RNA transcripts, they include only some chunks of genetic material known as exons and throw out the rest.

10 Feb 2023

Marine plankton samples can help understand the link between ocean pollution and chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

9 Jan 2023

What are the implications of microbiome-directed measures to treat type 2 diabetes?

According to preliminary findings from an ongoing, prospective study headed by Cedars-Sinai researchers, one type of bacteria seen in the gut might contribute to the development of Type 2 diabetes, while another might guard against the condition.

5 Jan 2023

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022

Study shows how probiotic bacteria may lower the risk of ER+ breast cancer

A new study presented at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga., suggests that probiotic bacteria may improve the anti-cancer actions of the breast cancer drug tamoxifen as well as other endocrine-targeted therapies, potentially lowering the risk of estrogen receptive positive (ER+) breast cancer.

13 Jun 2022

Gene expression analysis helps identify genes that cause endocrine resistance in breast cancer

The most prevalent type of cancer detected in women is breast cancer (BC). BC is the second biggest cause of death among female cancer patients globally.

9 Jun 2022

Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022