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Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

The virus wreaking havoc on our lives is an efficient infection machine. Comprised of only 29 proteins (compared to our 400,000), with a genome 1/200,000 the size of ours, SARS-CoV-2 is expertly evolved to trick our cells to contribute its machinery to assist in its propagation.

22 Oct 2020

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Ancient embedded elements in our DNA from generations past can activate a powerful immune response to kill cancer cells like an infection.

22 Oct 2020

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

SARS-CoV-2 has been shown to enter cells by interaction with ACE2, which is found on the surface of cells in the lungs and throughout the body.

21 Oct 2020

New strategy for capturing interactions among glycans and protein activators in live cells

Human cells are encased by a membrane coated with diverse sugar molecules known as glycans. These glycans play many roles in health and disease, making them important to understand.

20 Oct 2020

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

Knowing you have developed antibodies against the SARS-CoV-2 virus after recovering from COVID-19 doesn't tell you everything about your immunity.

20 Oct 2020

A new look at an old technique for studying protein dynamics

A fresh new look at an old technique in protein biochemistry has shown that it should be reintroduced to the spectroscopy toolkit.

20 Oct 2020

Researchers develop new approach that uses DNA-synthesizing biological enzyme

According to current estimates, the amount of data produced by humans and machines is rising at an exponential rate, with the digital universe doubling in size every two years.

19 Oct 2020

Army researchers test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale. Their method holds promise for accurately identifying potential donors who have the best chance of helping infected patients through convalescent plasma therapy.

15 Oct 2020

Statins can reduce risk of heart attacks and other cardiovascular diseases

According to a study recently published in the eLife journal, cholesterol-lowering drugs, known as statins, may lower cancer risk in humans via a pathway unassociated with cholesterol.

15 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Enzyme News and Research

Scientists use molecular dynamics simulations to reveal the secrets of SARS-CoV-2 virus

Ancient embedded elements in human DNA can activate powerful immune response to kill cancer cells

Researchers uncover a new cellular mechanism for disposing of misfolded proteins

New DNA-cutting tool could advance gene editing for novel treatments

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

New strategy for capturing interactions among glycans and protein activators in live cells

Scientists develop novel lab testing procedure for detection of SARS-CoV-2 antibodies

A new look at an old technique for studying protein dynamics

Researchers develop new approach that uses DNA-synthesizing biological enzyme

Army researchers test alternative ways to measure COVID-19 antibody levels

Statins can reduce risk of heart attacks and other cardiovascular diseases

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Cyanobacteria As "Green" Catalysts In Biotechnology

Imaging technique could replace invasive tissue biopsies to determine cancer drug resistance

Researchers reveal mechanism behind osimertinib resistance in some lung-cancer patients

Researchers demonstrate new method to increase catalytic activity of cyanobacteria

Deep learning-based technique could boost drug development

Understanding beta-cell growth mechanisms may help treat metabolic diseases

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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