Ferroptosis News and Research

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Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

29 Jun 2023

Blocking Necroptosis Could Lead to the Inhibition of Cancer Metastasis

A new editorial paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, "Tumor necroptosis promotes metastasis through modulating the interplay between tumor and host immunity."

25 Apr 2023

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Glioblastoma is the most prevalent kind of adult brain tumor.

10 Apr 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

This study is led by Dr. Anjian Xu (Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University), Dr. Min Cong (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) and Dr. Junying Ding (Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University).

20 Feb 2023

Innovative cancer therapy options with new cell death mechanism

Researchers from The University of Texas MD Anderson Cancer Center have described a previously unrecognized type of cell death called disulfidptosis in a study that was published in Nature Cell Biology.

7 Feb 2023

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

Ferroptosis News and Research

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Blocking Necroptosis Could Lead to the Inhibition of Cancer Metastasis

Specialized Diet Stimulates a Unique Form of Programmed Cell Death

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

Innovative cancer therapy options with new cell death mechanism

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

High levels of polyunsaturated fatty acids in liver cells linked to hepatitis C virus resistance

Study reveals mitochondrial enzyme plays a vital role in preventing ferroptosis

Study identifies a promising target for cancer treatment

Fatty acid can kill cancer cells, study shows

'Cells-Soldiers' Turned To Be More Resistant Than 'Cells-Combat Medics'

The Exclusome, A New Mammalian "Containter"

Breaking Down the Onso System: PacBio's Genomic Advancement

The Last Piece of Our Genome: Sequencing the Y Chromosome

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