Fibroblast News and Research

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Fibroblasts are connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.

Tumor progression after immunotherapy: Molecular pathways revealed

The University of Michigan’s Rogel Cancer Center researchers discovered a mechanism that explains why a subset of patients’ tumors grows rather than shrink when treated with immunotherapy.

20 Jan 2023

New electrochemical sensing platform holds promise for monitoring perfusable vascular networks

The costliness of drug development and the limitations of studying physiological processes in the lab are two separate scientific issues that may share the same solution.

9 Nov 2022

New guidelines to generate high-quality, well-structured organoids

Researchers have opened a new avenue for investigations of neurological development, disease, and therapies that cannot be undertaken in living people by employing stem cells to grow small brain-like structures in the lab.

30 Sep 2022

Scientists discover cells travel faster through mucus than blood

Some cells travel quicker in thicker fluids, such as honey against water or mucus versus blood, because their ruffled edges detect the viscosity of their surroundings and adjust to boost their speed.

From University of Toronto 28 Jul 2022

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Scientists from Kumamoto University used next-generation sequencing to analyze human endogenous retrovirus (HERV) integration sites and found that these primitive retroviruses can retrotranspose (DNA sequence insertion with RNA mediation) into iPS cells.

31 May 2022

Reducing the amount of protein in diet produces an array of favorable health outcomes, study says

The lifespan extension caused by a low-protein diet appears to be coordinated by a single hormone.

18 May 2022

New protective mechanism against non-alcoholic fatty liver disease identified

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

High performance microplates for enhanced cell growth and survival

The Sero Krystal™ PDL range of coated microplates from Porvair Sciences set a new benchmark for reproducible cell culture even with challenging cell types.

From Porvair Sciences Limited 20 Apr 2022

Scientists discover a special cell in salivary glands that is likely crucial for oral health

Scientists at Scripps Research and the National Institute of Dental and Craniofacial Research have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.

13 Apr 2022

New technique for better visualizing the CNS fibroblasts

The central nervous system (CNS) consists of several types of cells having varied specialized functions.

7 Apr 2022

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

In a breakthrough discovery, scientists from The University of Texas Health Science Center at San Antonio today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure in adipose (fat) tissues and resulted in weight loss.

6 Apr 2022

A critical subset of supporting cells may lie at the origins of scleroderma

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Researchers gain better understanding of the fast signaling dynamics in stem cells

Divide, differentiate or die? Making decisions at the right time and place is what defines a cell's behavior and is particularly critical for stem cells of an developing organisms.

From The Max Planck Institute 25 Feb 2022

Researchers map the cellular landscape in diabetic foot ulcers

Diabetic foot ulcerations – open sores or wounds that refuse to heal – are a devastating complication affecting more than 15 percent of people with diabetes and resulting in more than 70,000 lower extremity amputations per year in the United States alone.

11 Jan 2022

Fibroblast News and Research

Tumor progression after immunotherapy: Molecular pathways revealed

New electrochemical sensing platform holds promise for monitoring perfusable vascular networks

New guidelines to generate high-quality, well-structured organoids

Scientists discover cells travel faster through mucus than blood

Endogenous retroviruses in the human genome are likely to pose a risk in regenerative medicine

Reducing the amount of protein in diet produces an array of favorable health outcomes, study says

New protective mechanism against non-alcoholic fatty liver disease identified

High performance microplates for enhanced cell growth and survival

Scientists discover a special cell in salivary glands that is likely crucial for oral health

New technique for better visualizing the CNS fibroblasts

Breakthrough discovery provides a desirable drug target to tackle metabolic diseases

A critical subset of supporting cells may lie at the origins of scleroderma

Researchers gain better understanding of the fast signaling dynamics in stem cells

Researchers map the cellular landscape in diabetic foot ulcers

CAR T cells produced in vivo using modified mRNA treat cardiac injury

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Study imparts mechanistic understanding on early stages of human cancer

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Induced pluripotent stem cells show promise to revive wildlife species

Study shows how brain protein helps pancreatic cancer cells to survive

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

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