Fluorescence Microscopy News and Research

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Fluorescence microscopy is an imaging technique used to examine cells and their internal components. Specific cellular components can be labeled with fluorophores.

New insights into the biology of chytrid fungus responsible for deadly skin infection

Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide.

9 Feb 2021

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

3 Feb 2021

Novel microscopy system for scanless 3D measurement with submicron resolution

The National Institute of Information and Communications Technology (NICT), Tohoku University, Toin University of Yokohama, and Japan Science and Technology Agency (JST) have succeeded in developing a scanless high-speed holographic fluorescence microscopy system with submicron resolution for a 3D space.

1 Feb 2021

Study shows TALEN is five times more efficient than CRISPR-Cas9 tool

Using single-molecule imaging, scientists have compared the CRISPR-Cas9 and TALEN genome editing tools.

28 Jan 2021

New approach to biomaterial production may ease environmental burden of forestry, agriculture

It takes a lot to make a wooden table. Grow a tree, cut it down, transport it, mill it ... you get the point. It's a decades-long process. Luis Fernando Velásquez-García suggests a simpler solution: "If you want a table, then you should just grow a table."

22 Jan 2021

Altered sugar composition impacts cell-to-surface adhesion

Biotechnologists measure the forces with which algae cells adhere to surfaces and move on them. How can cells adhere to surfaces and move on them? This is a question that was investigated by an international team of researchers headed by Prof. Michael Hippler from the University of Münster and Prof. Kaiyao Huang from the Institute of Hydrobiology (Chinese Academy of Sciences, Wuhan, China).

4 Jan 2021

Scientists develop novel approach to acquire fluorescence lifetime images

Fluorescence microscopy is widely used in biochemistry and life sciences because it allows scientists to directly observe cells and certain compounds in and around them. Fluorescent molecules absorb light within a specific wavelength range and then re-emit it at the longer wavelength range.

4 Jan 2021

Biochemist discovers hidden cellular machinery essential for higher-order life

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

7 Dec 2020

Researchers present holographic Raman microscopy for biological sensing applications

Raman spectroscopy is widely used in analytical sciences to identify molecules via their structural fingerprint. In the biological context, the Raman response provides a valuable label-free specific contrast that allows distinguishing different cellular and tissue contents.

1 Dec 2020

Chemists identify effective inhibitors to block the uptake of SARS-CoV-2

The cell membrane is impermeable to viruses: to get inside and infect a cell, they use a range of strategies to exploit the cellular and biochemical properties of the membranes.

23 Nov 2020

Study demonstrates utility of novel method in fluorescent labeling

Thirty years ago, the cloning of the green fluorescent protein GFP, together with genetic engineering tools, revolutionized the field by enabling researchers to fuse a fluorescent 'beacon' to any protein of interest so that it can be directly observed in living cells using fluorescence microscopy.

16 Nov 2020

Glass surface embedded with self-assembled gold nanoparticles can improve live-cell imaging

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.

9 Nov 2020

New research finds clues for disarming antibiotic-resistant bacteria

A virus can stop bacteria from sharing genes for antibiotic resistance among themselves, Texas A&M AgriLife researchers have discovered.

4 Nov 2020

UB biophysicist receives $2 million NIH grant to explore protein-RNA droplets

Inside human cells, proteins and RNA can cluster together to form spherical droplets that play vital roles in cellular processes as well as in certain human diseases.

23 Sep 2020

Study shows flotillin proteins have direct influence on cell membrane structure

Similar to all cells, bacteria have a membrane that protects them from the outside just like skin.

20 Jul 2020

Study reveals the role of Rubisco enzymes in carbon-fixing machinery of cyanobacteria

Researchers from the University of Liverpool have provided a new understanding of how cyanobacteria build the organelles that are crucial for their potential to photosynthesize.

13 Jul 2020

Protein PRC1 acts as a 'viscous glue' during cell division, research shows

An over-abundance of the protein PRC1, which is essential to cell division, is a telltale sign in many cancer types, including prostate, ovarian, and breast cancer.

8 Jul 2020

Scientists develop novel image processing techniques to reduce processing time

Researchers have created novel image processing techniques for microscopes that can decrease the time for post-processing by up to several thousand-fold.

1 Jul 2020

New imaging techniques reveal individual transcription factor proteins in real time

A new study provides a new understanding of the mechanisms through which DNA-binding proteins look for the genome for their particular binding sites.

26 Jun 2020

Researchers create 3D fluorescence and phase imaging of living cells based on digital holography

A research group led by Kobe University's Professor MATOBA Osamu (Organization for Advanced and Integrated Research) has successfully created 3D fluorescence and phase imaging of living cells based on digital holography.

2 Jun 2020