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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Identification of a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

9 Feb 2022

Cell culture environments are unstable and drive reproducibility crisis

Culture environments of different cell types growing in culture vessels or Petri dishes vary significantly from each other and from conditions in the living body, potentially driving the "reproducibility crisis" in biomedical research, according to a team of KAUST bioscientists.

9 Feb 2022

Gene-editing techniques could be used to tackle mitochondrial disorders, study shows

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

9 Feb 2022

Epigenetic inheritance enhances mating in stressed out C. elegans

Sexual reproduction allows organisms to mix up their genes and develop new adaptations to survive a harsh and ever-changing environment.

8 Feb 2022

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

There are many different ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops.

8 Feb 2022

Scientists use genetically informed brain atlases to identify hundreds of genomic loci

An international team of scientists has used atlases of the human brain informed by genetics to identify hundreds of genomic loci. Loci is plural for locus, and in genetics indicates the physical location of a gene or variant on a chromosome.

From UC San Diego 8 Feb 2022

TAB1 gene plays a key role in maintaining stem cells during ovule formation in rice plants

Rice has long been a staple food for more than half the global population. The United Nations even declared 2004 the International Year of Rice to raise awareness and encourage action to protect and advance the crop for a rapidly growing population.

7 Feb 2022

New gene therapy approach may help treat a wide variety of electrical heart diseases

Biomedical engineers at Duke University have demonstrated a gene therapy that helps heart muscle cells electrically activate in live mice.

7 Feb 2022

Scientists use CRISPRa to discover genes that play a role in immune cell biology

CRISPR genome editing has served as a powerful tool for deleting or altering DNA sequences and studying the resulting effect.

4 Feb 2022

New method helps distinguish bacterial DNA from human and other non-bacterial cells

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

4 Feb 2022

Largest genome study identifies new genetic risk factors for migraine

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine.

4 Feb 2022

Research focuses on how short-term genetic memories can be inherited across generations

A gene-silencing tool could enable new opportunities for advancing basic biomedical research and drug development.

4 Feb 2022

Human rRNA genes differed based on a person’s geographic ancestry

Genome research that explored gene variants that are considered a crucial building block for protein-synthesizing microscopic structures took an unexpected turn.

4 Feb 2022

Microorganisms “breathe” rocks through extracellular electron transfer, says study

Microbes may be tiny, yet they have a significant influence on the Earth’s habitability.

4 Feb 2022

Different autism risk genes have similar effects on brain development, study finds

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

3 Feb 2022

Flavanols enhance browning of adipose tissue by activating the sympathetic nervous system

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

3 Feb 2022

Using AI solutions to predict cell fates

Data is not only the answer to numerous questions in the business world; the same applies to biomedical research. In order to develop new therapies or prevention strategies for diseases, scientists need more and better data, faster and faster.

3 Feb 2022

Study reveals a deficiency in soil bacterial recovery following revegetation

Restoration of degraded landscapes requires time and patience, but researchers, comparing the outcomes of a six-year native planting initiative in South Australia, were shocked by persistent soil deficiencies.

2 Feb 2022

Researchers provide first evidence of the gene-environment interaction in the social dysfunctions typical of autistic disorders

Autism spectrum disorders are characterized by a wide range of behavioral issues.

2 Feb 2022

Gene News and Research

Further Reading

Identification of a bivalent histone-mark switch essential for angiogenesis

Cell culture environments are unstable and drive reproducibility crisis

Gene-editing techniques could be used to tackle mitochondrial disorders, study shows

Epigenetic inheritance enhances mating in stressed out C. elegans

Researchers make new advances in connecting the evolution of pregnancy and cancer metastasis

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

Scientists use genetically informed brain atlases to identify hundreds of genomic loci

TAB1 gene plays a key role in maintaining stem cells during ovule formation in rice plants

New gene therapy approach may help treat a wide variety of electrical heart diseases

Scientists use CRISPRa to discover genes that play a role in immune cell biology

New method helps distinguish bacterial DNA from human and other non-bacterial cells

Largest genome study identifies new genetic risk factors for migraine

Research focuses on how short-term genetic memories can be inherited across generations

Human rRNA genes differed based on a person’s geographic ancestry

Microorganisms “breathe” rocks through extracellular electron transfer, says study

Different autism risk genes have similar effects on brain development, study finds

Flavanols enhance browning of adipose tissue by activating the sympathetic nervous system

Using AI solutions to predict cell fates

Study reveals a deficiency in soil bacterial recovery following revegetation

Researchers provide first evidence of the gene-environment interaction in the social dysfunctions typical of autistic disorders

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