Genetic News and Research

RSS

Imported Seafood and the Spread of Colistin Resistance

Findings show imported seafood as a potential source of colistin-resistance genes, underscoring the urgency of addressing antimicrobial resistance globally.

23 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025

Scientists Reveal Molecular Battle Between Maternal and Paternal Genes in Bees

Despite having identical genetic instructions, female honey bee larvae can develop into either long-lived reproductive queens or short-lived sterile workers who help rear their sisters rather than laying their own eggs.

23 Jun 2025

Anthrobots Reveal How Cells Can Build New Shapes Without Genetic Edits

Modern humans have existed for over 200,000 years, and each new generation has begun with a single cell-dividing, changing shape and function, organizing into tissues, organs, and limbs.

23 Jun 2025

In Vivo CAR T Cell Generation Shows Promise for Cancer and Autoimmune Diseases

Researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells.

20 Jun 2025

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

The study identifies genetic variants influencing colorectal cancer risk through DNA methylation, suggesting new avenues for targeted screening and prevention.

20 Jun 2025

Organotypic Model of the Human Gut Epithelium Demonstrates Genetic Determinants of Shigella Colonization

A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early infection.

20 Jun 2025

Hundreds of Human Genes Found to Act Like On Off Switches

Gene expression, where cells use the genetic information encoded in DNA to produce proteins, has been thought of as a dimmer light.

19 Jun 2025

New Australian Chickpea Pan-Genome Poised to Boost National Chickpea Production

Researchers from the Centre for Crop and Food Innovation (CCFI) at Murdoch University have led the generation of a pan-genome tailored specifically to Australian chickpea varieties, paving the way for improved chickpea production across the country.

19 Jun 2025

Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

19 Jun 2025

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.

18 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Bacteria Use Harpoon-Like Weapons to Kill and Eat Their Neighbors

Bacteria are microscopic murderers. We've long known that bacteria kill each other, it's part of microbial life.

17 Jun 2025

Study Finds Shared Brain Signature Across Autism Variants

New research from the University of Minnesota Medical School suggests that different genetic forms of autism may lead to similar patterns in brain activity and behavior. The findings were recently published in Nature Neuroscience.

16 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Shared Brain Activity Patterns in Diverse Genetic Forms of Autism

Research from the University of Minnesota identifies common neural patterns in autism, suggesting genetic variants influence brain activity and behavior.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

New Genetic Marker Panel Aims to Save Koalas from Extinction

Standardized genetic testing for koalas at UQ is a game-changer for conservation, improving collaboration and understanding of genetic diversity in populations.

13 Jun 2025