Genetic News and Research

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Targeting RNA Polymerase 1 Rewires Cancer Cell Splicing and Halts Growth

Researchers at the Johns Hopkins Kimmel Cancer Center and Department of Radiation Oncology and Molecular Radiation Sciences uncovered a new tumor-suppressive response that could lead to novel therapies targeting hard-to-treat cancers.

19 Jun 2025

Quantifying Breast Cancer Heterogeneity Through Single-Cell Transcriptomics

Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels.

18 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

Bacteria Use Harpoon-Like Weapons to Kill and Eat Their Neighbors

Bacteria are microscopic murderers. We've long known that bacteria kill each other, it's part of microbial life.

17 Jun 2025

Study Finds Shared Brain Signature Across Autism Variants

New research from the University of Minnesota Medical School suggests that different genetic forms of autism may lead to similar patterns in brain activity and behavior. The findings were recently published in Nature Neuroscience.

16 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Shared Brain Activity Patterns in Diverse Genetic Forms of Autism

Research from the University of Minnesota identifies common neural patterns in autism, suggesting genetic variants influence brain activity and behavior.

16 Jun 2025

Study Reveals RNA Polymerase I Stalling Mechanism at Abasic DNA Damage Sites

New study shows RNA polymerase I halts at abasic DNA damage, helping prevent faulty rRNA production and exposing lesions for repair in dividing cells.

16 Jun 2025

Frog Egg Extracts Illuminate the Untangling Mechanism of DNA Knots

Research reveals how G-quadruplex DNA structures are untangled, highlighting a role for RNA in genome stability and potential cancer therapy strategies.

13 Jun 2025

New Genetic Marker Panel Aims to Save Koalas from Extinction

Standardized genetic testing for koalas at UQ is a game-changer for conservation, improving collaboration and understanding of genetic diversity in populations.

13 Jun 2025

Flipped DNA Segments Help Fish Rapidly Evolve into New Species

Researchers have found that chunks of 'flipped' DNA can help fish quickly adapt to new habitats and evolve into new species, acting as evolutionary 'superchargers'.

13 Jun 2025

Integrating Imaging and Molecular Profiling to Transform Treatment of Intrahepatic Cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Metagenomic Study Examines Combined Effects of Global Change on Soil Microbes

Metagenomic analysis shows that combined global change factors reshape soil microbial composition and function, highlighting limits of single-stressor studies.

12 Jun 2025

New Frontier in Understanding Brain Development and Rare Diseases

A groundbreaking study identifies unknown genetic disorders affecting brain development, offering new insights into neurodevelopmental conditions and diagnoses.

11 Jun 2025

Study Identifies Key Yield Traits in Complex Banana Genome

Banana breeding is notoriously difficult. Most cultivated bananas are sterile triploids with limited recombination and long growth cycles.

11 Jun 2025

Electro-bioprinting as a Tool to Study Early Human Embryonic Development

Bioprinted epiblast-like structures mimic early human embryonic development, offering a scalable, ethical platform to study gastrulation and tissue formation.

11 Jun 2025

The Role of Metabolism in Bacterial Survival and Resistance

Ciprofloxacin induces bioenergetic stress in E. coli, boosting survival rates and resistance development. Metabolic shifts challenge antibiotic effectiveness.

10 Jun 2025

Mapping the Genetic Blueprint of Flowering Chinese Cabbage

Flowering Chinese cabbage (Brassica rapa ssp. chinensis var. parachinensis), known for its tender stalks and vibrant greens, has long been a dietary mainstay in southern China and beyond.

9 Jun 2025

Myosin XI Helps Plants Absorb Boron Under Nutrient Stress

Boron, though required only in minimal amounts, is vital for plant development. It strengthens cell walls and supports the growth of roots and shoots.

9 Jun 2025