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Scientists decode humans’ adaptations to historical coronavirus outbreaks

An international research team, jointly headed by the University of Adelaide and the University of Arizona, has examined the genomes of over 2,500 modern humans from 26 global populations to gain a better understanding of people’s adaptations to the historical outbreaks of coronavirus.

25 Jun 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

Researchers identify key cells involved in childhood brain cancer

A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.

25 Jun 2021

New methodology assesses whole-genome sequencing data of SARS-CoV-2 mutations

According to researchers from Harvard T.H. Chan School of Public Health and MIT, the use of genome-wide association studies (GWAS) methodology to assess whole-genome sequencing data of SARS-CoV-2 mutations and COVID-19 mortality data can help identify highly pathogenic variants of the virus that should be flagged for containment.

25 Jun 2021

New airway model boosts COVID-19 research

A research team has successfully built a model of lung cells that can be used to simulate how COVID-19 infects the airways.

22 Jun 2021

Groundbreaking field trials underscore the potential of gene-editing technology

Field trials that explore healthy chemicals in agronomically significant brassica crops have underscored the “immense potential” of gene-editing technology.

22 Jun 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

Presence of certain stem cells correlates with non-genetic resistance mechanisms to cancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Molecular breeding can enhance the quality of olives

Olives, well-known for their characteristic bitter taste, are in high demand owing to the popularity of the oil that's derived from them.

17 Jun 2021

Plants evolve defensive systems through a combination of environmental factors

According to research plants acquire unique defensive compounds through the collective effects of genes, geography, and environmental circumstances.

17 Jun 2021

Study reveals the key role of motor proteins in mitotic spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells has been unknown, until now!

16 Jun 2021

New method reveals high-resolution structure of biomolecules

A new study integrates molecular dynamics simulations and experimental data to inspect biomolecules in their natural environment.

16 Jun 2021

Researchers identify genetic variant discrepancies between two genome references

Advances in technology have supported the development of updated reference genomes used for sequencing ever since the Human Genome Project.

16 Jun 2021

Single mutation leads to rare genetic muscle disease

The origin of rare, severe muscle disease has been uncovered by an international team of researchers headed by the University of Bonn (Germany).

16 Jun 2021

Ethnically diverse genetic study expands understanding about potential causes of type 2 diabetes

Researchers at the Keck School of Medicine (KSOM) of USC are among the contributors to a large-scale ethnically diverse genetic study that has expanded what we know about potential causes of type 2 diabetes.

15 Jun 2021

How to stop the alarming decline in nature's genetic diversity

AZoLifeSciences speaks to Sean Hoban and Colin Khoury about the decline in natures genetic diversity and how we can work to protect it.

15 Jun 2021

Study reveals molecular factors that allow birds to fly

For many years, researchers, adventure-seekers, and aeronautical designers have attempted to simulate the characteristics that enable birds to fly, particularly balance and wing structure.

15 Jun 2021

Misfolded tau proteins cause progressive degeneration in Alzheimer's disease

According to a study performed by researchers from the Van Andel Institute and the University of Pennsylvania, misfolded proteins that impair neurons in Alzheimer’s disease travel the “roads” of the brain, similar to a supply truck crossing the countryside.

11 Jun 2021

Study sheds new light on the early stages of viral evolution

Scientists from the Universities of York and Leeds, in association with Hilvert Laboratory at the ETH Zurich, have investigated the evolution, structure, and assembly of virus-like particles. According to the researchers, this breakthrough discovery will impact the way viruses are treated in the future.

11 Jun 2021

Scientists unravel the proteins that trigger some cancerous tumors

Even on a good day, DNA is constantly getting damaged. Nicks, scratches, breaks: the delicate strands that carry life's genetic code take a beating as they jumble about in the course of their work. If left untreated, errors accumulate, with fatal consequences -- such as cancerous tumors -- for the cell and the organism.

11 Jun 2021