Glycan News and Research

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New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Potential SARS-CoV-2 therapy based on banana protein

A study praising the development of a potential treatment that might be applied to combat all recognized influenza strains was published online on January 13th, 2020.

25 Oct 2022

Study shows how gut bacteria feed on carbohydrate attached to plant proteins

A carbohydrate commonly found attached to plant proteins is a food source for the bacteria in our gut, new research suggests.

23 Sep 2022

Researchers find why SARS-CoV-2 does not spread easily from surfaces

Early in the pandemic, many people fastidiously disinfected surfaces because laboratory studies predicted that SARS-CoV-2 could be easily transmitted in this way.

3 Mar 2022

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Antibody-drug conjugates, an intricate that covalently links a potent cytotoxin to an antibody, have piqued the interest of researchers as a new bio-therapeutic methodology.

14 Feb 2022

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

While dendritic cell immunoreceptor (DCIR) is known to mediate inflammation and bone metabolism, ligands that bind DCIR and the mechanisms underlying DCIR activity remain poorly understood.

From Tokyo University of Science 25 Nov 2021

Study employs AI to comprehend sugar surrounding proteins in the human body

Novel studies on artificial intelligence (AI) algorithms facilitated researchers to develop more complete models of the protein structures in human bodies.

8 Nov 2021

Study provides insights on mucin degradation mechanisms by a group of gut bacteria

Recent research identified that a single sulfatase adds to the degradation of mucus that safeguards the intestinal lining.

13 Oct 2021

Waters BioAccord System with ACQUITY Premier brings greater simplicity, accuracy and reproducibility to multi-attribute monitoring of biopharmaceuticals

Waters Corporation today introduced the Waters™ BioAccord™ System with ACQUITY™ Premier, a combination of the Waters BioAccord System and the breakthrough ACQUITY Premier UPLC™ with MaxPeak™ High Performance Surface technology.

From Waters Corporation 17 Sep 2021

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

From UC San Diego 20 Aug 2021

AI model helps predict which viruses are likely to spread from animals to humans

A new model that applies artificial intelligence to carbohydrates improves the understanding of the infection process and could help predict which viruses are likely to spread from animals to humans. This is reported in a recent study led by researchers at the University of Gothenburg.

16 Jun 2021

New kind of biomolecule could play a vital role in the biology of all living things

Stanford researchers have discovered a new kind of biomolecule that could play a significant role in the biology of all living things.

18 May 2021

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

A new study has shown that it is viable to reduce tumor growth by a therapy that involves tagging cancer cells with various therapeutic molecules.

26 Apr 2021

Study reveals how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively. The insights may be helpful for developing effective therapies.

16 Apr 2021

Study provides insight into the structure of prion proteins responsible for diseases

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

22 Feb 2021

Glycan News and Research

New antibody "cocktail" may help counter the Lassa virus

Potential SARS-CoV-2 therapy based on banana protein

Study shows how gut bacteria feed on carbohydrate attached to plant proteins

Researchers find why SARS-CoV-2 does not spread easily from surfaces

SARS-CoV-2 spike protein can specifically recognize the terminal sialic acid on sugars

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Research could help understand DCIR's role in the pathogenesis of autoimmune diseases

Study employs AI to comprehend sugar surrounding proteins in the human body

Study provides insights on mucin degradation mechanisms by a group of gut bacteria

Waters BioAccord System with ACQUITY Premier brings greater simplicity, accuracy and reproducibility to multi-attribute monitoring of biopharmaceuticals

Researchers discover how glycans act as gateways for SARS-CoV-2 entry

AI model helps predict which viruses are likely to spread from animals to humans

New kind of biomolecule could play a vital role in the biology of all living things

Therapy using artificial metalloenzymes helps reduce tumor growth, finds study

Study reveals how some antibodies can effectively disable ebolaviruses

Study provides insight into the structure of prion proteins responsible for diseases

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Computational study of the structure and dynamics of glycosylated SARS-CoV-2

New strategy for capturing interactions among glycans and protein activators in live cells

SARS-CoV-2 may induce long-term autoimmune disorder due to self-glycan antibody production

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

Genome Editing Has A New Code

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