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DNA Organization Offers Clues for Advancing Stem Cell Therapy

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power. The researchers demonstrate in a paper published in the journal Genes & Development that these cells rely on a group of helper proteins called histone chaperones — organizers or guides known to help package our two-meter-long genome when cells need to divide or switch on specific genes.

22 Apr 2025

New Atlas of Chicken Genetics May Help Breed Disease Resistant Birds

An international team of researchers led by Professor Huaijun Zhou from the UC Davis Department of Animal Science has created the first-ever detailed map of how genes are regulated in chickens - a breakthrough that could help scientists breed birds that are more resistant to diseases like avian influenza.

10 Apr 2025

New Protein Identified as Regulator of Mitochondrial Calcium Transport

Calcium transport into and out of mitochondria – the powerhouses of cells – is central to cellular energy production and cell death.

9 Apr 2025

Study Sheds Light on Evolutionary Role of Microglia in the Peripheral Nervous System

In a study published in Cell on April 7, a research team led by Prof. Li Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence of microglia in the peripheral nervous system (PNS) and identified their crucial role in regulating neuronal soma size throughout evolution.

8 Apr 2025

Innovative Imaging Technique Tracks Cellular Processes with Minimal Damage

An advancement in imaging technology has the potential to revolutionize the understanding of the inner workings of living cells and offer insights into a variety of diseases.

3 Apr 2025

New Genetic Targets for Atherosclerosis Prevention

Genetic variations that raise the risk of atherosclerosis have been found by Swedish researchers.

1 Apr 2025

MIT Scientists Use Light to Control Cell Movement in Starfish

Life takes shape with the motion of a single cell. In response to signals from certain proteins and enzymes, a cell can start to move and shake, leading to contractions that cause it to squeeze, pinch, and eventually divide.

25 Mar 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Early Embryo Development May Be the Foundation for Lifelong Health

Researchers at the University of Adelaide have found that the initial stages of embryo development significantly influence an individual's future health and aging.

19 Mar 2025

Calcium-Mediated Electrical Communication in Epithelial Cells

For a long time, it was believed that only nerve and heart cells utilized electrical impulses for communication, while epithelial cells which form the linings of human skin, organs, and body cavities were considered silent, primarily acting as protective barriers that absorb and secrete various substances.

18 Mar 2025

New Discovery in RNA Splicing Could Transform Treatment of Aggressive Cancers

Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film.

17 Mar 2025

Spotiphy Revolutionizes Spatial Transcriptomics with AI for Single-Cell Resolution

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue.

14 Mar 2025

Generative AI Enhances Spatial Gene Expression Analysis in Tissue Samples

Spatial transcriptomics is an advanced technique that analyzes gene expression within tissue sections, such as those from the heart, skin, or liver. These analyses offer valuable insights into how spatial organization influences cellular functions across various biological contexts and diseases.

13 Mar 2025

Modeling Genetic Disruptions in Heart Development

In the process of heart development, cells move around and interact with one another to establish their positions, with significant implications: pairing with an incorrect cell can determine whether the heart functions properly or not.

13 Mar 2025

Study Explores the Physiological Role of Nwd1 Gene in MASH Pathogenesis

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

12 Mar 2025

Scientists Develop Off-the-Shelf Vascular Grafts Using Stem Cells

Zhang, J., et al. (2025) Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model. Cell Reports Medicine. doi.org/10.1016/j.xcrm.2025.102002.

12 Mar 2025

Lack of Genetic Diversity in Reference Groups Leads to Misdiagnoses

A new study has uncovered that a gene variant common in Oceanian communities was misclassified as a potential cause of heart disease, highlighting the risk of the current diversity gap in genomics research which can pose a greater risk for misdiagnosis of people from non-European ancestries.

8 Mar 2025

Lactylation Levels Influence Cardiac Development and Regeneration in Mice

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

3 Mar 2025

New AI-Based Device Makes Flow Cytometry Affordable and Accessible

A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry ⎯ a technique used to analyze cells or particles in a fluid using a laser beam ⎯ affordable and accessible.

3 Mar 2025