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AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego. The benchmark finding, published in Genomic Medicine, foreshadows the next phase of medicine, where technology helps clinicians quickly determine the root cause of disease so they can give patients the right treatment sooner.

From The University of Utah 18 Oct 2021

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Cambridge researchers have discovered how T cells – an important component of our immune system – are able keep on killing as they hunt down and kill cancer cells, repeatedly reloading their toxic weapons.

15 Oct 2021

Mutant clones outcompete and eliminate early tumors, mouse study shows

Cells carrying mutations can out compete early tumors in the mouse esophagus, so they never make it into cancers, new research has shown.

15 Oct 2021

Study reveals gene responsible for food-dependent form of Cushing's Syndrome

A team of scientists in Montreal and Paris has succeeded in identifying the gene responsible for the development of a food-dependent form of Cushing's Syndrome, a rare disease affecting both adrenal glands.

15 Oct 2021

Study finds higher levels of air pollutants in regions near oil and gas wells

In a 14-year analysis of air quality across California, Stanford researchers observed higher levels of air pollutants within 2.5 miles of oil and gas wells, likely worsening negative health outcomes for nearby residents.

13 Oct 2021

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

12 Oct 2021

Researchers unravel impacts of protein BRD4 on how DNA folds

Recent research enhances the understanding of certain cancers and complex congenital disorders.

8 Oct 2021

Color-coded nutrition labels and warnings may encourage more healthful purchases

A new analysis has integrated findings from 134 studies of the impact of color-coded nutrition labels and warnings found on the front of some food packaging, indicating that these labels do indeed appear to encourage more healthful purchases.

7 Oct 2021

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

New research published in The Journal of Physiology has shown that ketone supplements may be a novel therapeutic strategy for protecting and improving brain health in people with obesity.

5 Oct 2021

Chula researchers develop a heathy food for noodle lovers with Udon and Vermicelli products

Researchers from the Faculty of Allied Health Sciences, Chulalongkorn University, are pleasing noodle lovers with Udon and Vermicelli products made from 100 percent egg white that are high in protein, low in fat, and gluten-free, suitable for health lovers and those who wish to control their weight, the elderly, people with certain diseases, and cancer patients

1 Oct 2021

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Researchers elucidate why certain drugs, in clinical trials, for treating a kind of acute myeloid leukemia often fail and revealed a means to restore their efficacy.

1 Oct 2021

Stringent lineage tracing crucial for studies of nerve cell regeneration

UT Southwestern stem cell scientists find that stringent lineage tracing is crucial for studies of nerve cell regeneration. Their results, which are published in Cell, show that this tracing is far from routine in the field and suggest that earlier studies reporting "striking" regeneration results must be reexamined.

30 Sep 2021

Tree health linked to great tits' phenological response to climate change

New Research from Oxford University has revealed that shifts in the timing of egg laying by great tits in response to climate change vary markedly between breeding sites within the same woodland and that this variation is linked to the health of nearby oak trees.

29 Sep 2021

Radiation therapy can reprogram heart muscle cells to a younger state, suggests study

New research from Washington University School of Medicine in St. Louis suggests that radiation therapy can reprogram heart muscle cells to what appears to be a younger state, fixing electrical problems that cause a life-threatening arrhythmia without the need for a long-used, invasive procedure.

27 Sep 2021

Researchers identify new protein that may critically contribute to severe COVID-19

The University of Kent's School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, have identified a protein that may critically contribute to severe forms of COVID-19.

27 Sep 2021

How do genetic variants influence the expression of genes in the blood?

Researchers are now pursuing intensive research on the genetic causes of traits and diseases, with over 250,000 such links known currently.

24 Sep 2021

Food insecurity increased early in the pandemic, mostly among families with children

Nearly 15 percent of U.S. households-;and nearly 18 percent of households with children-;reported food insecurity early in the COVID-19 pandemic, according to a survey conducted via social media by researchers at NYU School of Global Public Health.

From New York University (NYU) 23 Sep 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Heart News and Research

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

Researchers uncover how killer T cells repeatedly reload their toxic weapons to keep on killing

Mutant clones outcompete and eliminate early tumors, mouse study shows

Study reveals gene responsible for food-dependent form of Cushing's Syndrome

Study finds higher levels of air pollutants in regions near oil and gas wells

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

Researchers unravel impacts of protein BRD4 on how DNA folds

Color-coded nutrition labels and warnings may encourage more healthful purchases

Ketone supplement may be a new therapeutic strategy for enhancing brain health in adults with obesity

Chula researchers develop a heathy food for noodle lovers with Udon and Vermicelli products

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Stringent lineage tracing crucial for studies of nerve cell regeneration

Tree health linked to great tits' phenological response to climate change

Radiation therapy can reprogram heart muscle cells to a younger state, suggests study

Researchers identify new protein that may critically contribute to severe COVID-19

How do genetic variants influence the expression of genes in the blood?

Food insecurity increased early in the pandemic, mostly among families with children

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

Researchers seek to point a way toward a unified theory for DNA folding

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