Herpes is an infection caused by two different but closely related viruses — herpes simplex virus type 1 (HSV-1) or cold sores and herpes simplex virus type 2 (HSV-2) or genital herpes. Both are easy to catch. They have similar symptoms (blisters or sores) and both can occur on different parts of the body. When the infection is on the mouth, it is called oral herpes. When it is on or near the sex organs, it is called genital herpes. There is no cure for herpes. Treatments are available to speed up the healing of the genital sores.
In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).
In the human body, virus particles are identified by pattern recognition receptors (PRRs) either within or on the cell surface. When a receptor is activated, a signaling cascade is initiated, which results in the production and release of signaling molecules like interferons and cytokines.
A new editorial was published in Genes & Cancer on January 19th, 2023, entitled, "Severe herpesvirus infection beats adult T-cell leukemia/lymphoma."
Rutgers researchers have devised a new way to prevent viral infections: a live-attenuated, replication-defective DNA virus vaccine that utilizes the substance centanamycin to create an altered virus for vaccine development.
The overuse of antibiotics has forced microorganisms to evolve defenses against this kind of treatment. Antibiotic resistance is a problem that the WHO now views as one of the major hazards to human health.
According to a new study, the cornea creates a sensitive and restricted immune response to combat infections without causing visual damage.
Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.
Scientists from the University of Córdoba have been investigating the changes that occur in the T lymphocytes of the immune system with increasing age.
Recent research by scientists from the University of Illinois demonstrates a process that halts the herpes simplex virus 1 from inducing severe brain damage and death.
According to psychologists, in addition to our physiological immune system, we also have a behavioral one: an unconscious code of conduct that helps us stay disease-free, including fear and avoidance of unfamiliar - and so possibly infected - people.
Immunologists discovered how immune sensors in infected cells organize and initiate an immune response to infections with living bacteria and viruses.
In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.
As part of the drive to support junior research groups in research into infectious diseases, the Federal Ministry of Education and Research is to provide 2,162,188 euros in funding from 2021 to 2026 for the research project 'AGEnTS - Genetic Engineering of T-cells for Treating Infectious Diseases' at Friedrich-Alexander University Erlangen-Nürnberg (FAU).
Researchers have now used fluorescence images from live cells to train an artificial neural network to reliably detect cells that are infected by herpes viruses.
Scientists from the University of Illinois Chicago (UIC) have found that heparanase (HPSE) is an important regulator of innate defense mechanisms of cells.
Comprehensive identification of viral proteins encoded by viral genes is required to understand the pathophysiology of viral infections.
A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.
A new study shows how the immune system has a damaging effect on a severe brain condition, which is most commonly caused by the cold sore virus.
The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.
Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.