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Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Elevated levels of heart failure marker increase risk for diabetes-related complications

Healthy people - especially women - with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes.

19 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020

RNA-based therapeutic approach could be used to cure hereditary diseases

Short RNA molecules can be used as medication. Their effectiveness is based on the genetic information they carry: therapeutic RNA can bind to the body's own RNA and thus influence how it functions.

19 Aug 2020

Scientists identify complex enzyme that protects cells from constant DNA damage

A team of researchers have revealed the mechanism and 3D structure of a complex enzyme that guards cells against persistent DNA damage.

19 Aug 2020

Protective anti-prion antibodies found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies.

18 Aug 2020

Genome analysis helps identify 568 cancer driver genes

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver gene.

18 Aug 2020

Researchers show how two X chromosomes communicate during embryo development

Researchers at Massachusetts General Hospital (MGH) have solved a mystery that has long puzzled scientists: How do the bodies of female humans and all other mammals decide which of the two X chromosomes it carries in each cell should be active and which one should be silent?

18 Aug 2020

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

In a new study published in Cell Research, Chen-Yu Zhang's group at Nanjing University School of Life Sciences, China, reports that SIDT1 in the mammalian stomach mediates host uptake of dietary and orally administered microRNAs (miRNAs), thus exerting biological functions in the host.

18 Aug 2020

Study sheds light on genetic and molecular mechanisms involved in atopic dermatitis

The KIF3A gene contains common variants that raise the risk of a dysfunctional skin barrier and ultimately lead to a skin condition, called atopic dermatitis.

17 Aug 2020

NIH-supported research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

17 Aug 2020

Antibodies from natural controllers appear to play crucial role in eliminating hepatitis B virus

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

From Institut Pasteur 14 Aug 2020

Detection of cancer using different kind of liquid biopsy

Because cancer is easier to successfully treat when it's caught early, a major goal in cancer research is to develop new ways to find tumors at early stages, before they start to spread. One approach that's being studied are liquid biopsies.

14 Aug 2020

Single-cell analysis uncovers new details concerning mitochondrial diseases

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases-- inherited disorders that interfere with energy production in the body and currently have no cure.

14 Aug 2020

Hospital News and Research

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Elevated levels of heart failure marker increase risk for diabetes-related complications

Shielded stem cells can improve heart healing

RNA-based therapeutic approach could be used to cure hereditary diseases

Scientists identify complex enzyme that protects cells from constant DNA damage

Protective anti-prion antibodies found in humans

Genome analysis helps identify 568 cancer driver genes

Researchers show how two X chromosomes communicate during embryo development

SIDT1 in the mammalian stomach mediates absorption of dietary miRNAs

Study sheds light on genetic and molecular mechanisms involved in atopic dermatitis

NIH-supported research delineates how genetic variations cause atopic dermatitis

Antibodies from natural controllers appear to play crucial role in eliminating hepatitis B virus

Detection of cancer using different kind of liquid biopsy

Single-cell analysis uncovers new details concerning mitochondrial diseases

Researchers develop new drugs to eradicate parasitic worms

Aspirin may increase risk of disease progression in older adults with advanced cancer

Children exposed to cannabis in pregnancy have greater risk of autism

West Virginia University performs revolutionary Alzheimer's treatment

Surgical delays did not impact overall survival in patients with early stage breast cancer

Researchers are developing therapeutic treatments for acute stroke

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