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Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases.

3 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.

21 Jul 2023

Novel Drug Compound Reduces Sensory Hypersensitivity in Fragile X Mice

Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers.

14 Jul 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Whole Genome Sequencing More Effective Than Targeted Gene Sequencing in Detecting Genetic Disorders

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

12 Jul 2023

New Device Enables Real-Time Environmental Surveillance of SARS-CoV-2 Aerosols

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

11 Jul 2023

Mapping Immune Microenvironments in Human Placenta

Until recently, scientific evidence on the ability of SARS-CoV-2, the virus that causes COVID, to replicate in the human placenta has been inconclusive.

10 Jul 2023

EMBL-EBI Launches Pathogens Portal to Enhance Global Pathogen Surveillance

EMBL's European Bioinformatics Institute (EMBL-EBI) has launched the Pathogens Portal – an online platform that enables researchers, clinicians, and policymakers to access the most comprehensive collection of biomolecular data about pathogens.

7 Jul 2023

Nutrient Tug-of-War Between Tumor and Immune Cells Could Be Targeted for Cancer Therapy

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

6 Jul 2023

New Method Reveals How Hepatitis C Virus Evades Immune System

With a new method for examining virus samples researchers from the University of Copenhagen have solved an old riddle about how Hepatitis C virus avoids the human body's immune defenses.

6 Jul 2023

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

29 Jun 2023

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells.

29 Jun 2023

Immune Deficits in Space are Temporary

An increase in proof has been found that astronauts are highly vulnerable to infections while in space. For instance, astronauts on board the International Space Station (ISS) generally suffer from skin rashes, and also respiratory and non-respiratory diseases.

23 Jun 2023

New Genetic Marker Could Predict Lenvatinib Resistance in Hepatocellular Carcinoma

A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib.

23 Jun 2023

Loss of the Y Chromosome Impairs Body's Ability to Fight Cancer

According to recent Cedars-Sinai Cancer research, as men age, some of their cells lose the very feature that makes them biological males—the Y chromosome—and this loss impairs the body’s ability to fight cancer.

22 Jun 2023

Newly Found Disease Links Disruptions of Blood Formation, Immune System and Inflammation

In the quest to find the origin of the puzzling symptoms in four children, researchers from St. Anna Children's Cancer Research Institute, the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (ÖAW), and the Medical University of Vienna have discovered a completely new disease, linking disruptions of blood formation, the immune system, and inflammation.

22 Jun 2023

Hospital News and Research

Potential Strategies for Slowing Cognitive Deterioration in Age-Associated Neurodegenerative Conditions

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

Novel Drug Compound Reduces Sensory Hypersensitivity in Fragile X Mice

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

Whole Genome Sequencing More Effective Than Targeted Gene Sequencing in Detecting Genetic Disorders

New Device Enables Real-Time Environmental Surveillance of SARS-CoV-2 Aerosols

Mapping Immune Microenvironments in Human Placenta

EMBL-EBI Launches Pathogens Portal to Enhance Global Pathogen Surveillance

Nutrient Tug-of-War Between Tumor and Immune Cells Could Be Targeted for Cancer Therapy

New Method Reveals How Hepatitis C Virus Evades Immune System

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Immune Deficits in Space are Temporary

New Genetic Marker Could Predict Lenvatinib Resistance in Hepatocellular Carcinoma

Loss of the Y Chromosome Impairs Body's Ability to Fight Cancer

Newly Found Disease Links Disruptions of Blood Formation, Immune System and Inflammation

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