Infertility News and Research

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Infertility primarily refers to the biological inability of a person to contribute to conception. Infertility may also refer to the state of a woman who is unable to carry a pregnancy to full term.

Study Reveals Epigenetic Changes in Sperm from Non-Genetic Infertility Causes

How non-genetic factors can induce epigenetic modifications to the sperm and cause male infertility.

3 Jul 2024

Primitive Endoderm Stem Cells Offer New Hope for Fertility Treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

25 Jun 2024

High-Accuracy DNA Methylation Clocks Illuminate Age-Related Changes in Primate Ovaries

The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility.

5 Jun 2024

Stem Cell Factor Levels Show Promise in Predicting Successful IVF for Endometriosis

The ability of serum levels of stem cell factor to indicate the quality of oocyte and blastocyst development.

4 Jun 2024

New Insights into Human Embryonic Development Using Stem Cell Models

A new study using stem cell-based models has shed new light on how the human embryo begins to develop, which could one day benefit the development of fertility treatment.

3 Jun 2024

Sex-Specific Effects of Germline Regulation on Longevity and Repair in Vertebrates

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates.

17 May 2024

Nutrient Deprivation Induces Embryonic Diapause in Hungry Mouse Mums

It's challenging to sustain a pregnancy when food is short, or conditions are otherwise tough. That's why many mammalian embryos can postpone their growth to get through periods of environmental stress and then re-enter development when conditions improve.

12 Apr 2024

New Study Unveils Mechanism Behind Mice Ovary Development

Scientists at the Francis Crick Institute have provided insight into the proteins governing the development of mice's ovaries both prenatally and postnatally. This might help comprehend the progression of female infertility.

25 Mar 2024

How Does the Egg Coat Prevent Multiple Fertilization

The surrounding egg coat tightens once a sperm fertilizes an egg, mechanically blocking further sperm from entering and causing the embryo to die.

15 Mar 2024

Bulls Guide Research into Male Fertility Genetics

One in eight couples worldwide are unable to conceive within a year, or lifelong due to infertility, making it a common issue.

19 Feb 2024

High-Resolution Map Exposes Cellular Pathways to Fertility

An interdisciplinary team mapped the gene expression that takes place in mice during follicle maturation and ovulation using a state-of-the-art method of RNA tagging.

24 Jan 2024

Zipping Up Chromosomes: The Synaptonemal Complex Revealed

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

4 Jan 2024

Researchers Discover How Microbes Enhance Fruit Fly Reproduction

For many of us, when we think of microbiomes, our first thoughts are probably about the beneficial microorganisms that live in our guts.

26 Dec 2023

Understanding the Dynamic Regulation of Manchette Microtubules in Sperm Development

A team of researchers, led by Wenxiang Meng from the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences, has demonstrated that the deletion of the calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) gene in mice, which is associated with the minus ends of non-centrosomal microtubules, results in a condition known as oligoasthenoteratozoospermia.

6 Nov 2023

Towards A Better Understanding of Early Human Embryonic Development

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns.

22 Sep 2023

NC State Researchers Develop New Method to Produce Seedless Plants

North Carolina State University researchers have successfully transferred an important gene from one compartment of a plant cell to another to produce tobacco plants that lack pollen and viable seeds, while otherwise growing normally.

19 Sep 2023

New Insights into MCM8/9 Enzyme Could Lead to Treatments for Infertility and Cancer

Scientific research requires patience. The rewards are not always immediate, and the technology needed does not always exist. Michael A. Trakselis, Ph.D., professor and director of graduate affairs for the Department of Chemistry and Biochemistry at Baylor University, understands this.

30 Aug 2023