Infertility primarily refers to the biological inability of a person to contribute to conception. Infertility may also refer to the state of a woman who is unable to carry a pregnancy to full term.
Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied. Scientists have been working on creating in vitro models of human ovaries so that we can learn more about them and develop treatments for ovarian conditions, but most existing models use a combination of human and mouse cells, which do not faithfully replicate human ovary functions and take a long time to grow in the lab.
Iowa State University researchers may have solved a long-standing challenge associated with accelerated development of pure genetic lines.
Heavy metals such as lead and cadmium are present in batteries, cosmetics, food and other things that are part of everyday life.
At Cedars-Sinai, a special and elaborate molecular profile of endometriosis has been engineered by investigators to help enhance therapeutic options for the millions of women suffering from the disease.
Meiotic drivers, which are a sort of selfish gene, are, in fact, selfish. They are found in nearly all species’ genomes, including humans, and unfairly convey their genetic information to more than half of their offspring, resulting in infertility and impaired organism health.
According to scientists from the Georgia State University’s Institute for Biomedical Sciences, producing a mutation that impedes the way the bacterial pathogen Neisseria gonorrhoeae transmits gonorrhea might provide a novel means to prevent and treat the disease.
Sperm actually swim better together when they are swimming against the current. Contrary to common belief, spermatozoa frequently cooperate to go through the female reproductive system in a variety of mammalian species, contradicting the notion that the fastest and fittest male reproductive cell wins the fertilization race.
Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.
Chlamydia, the most common bacterial infection associated with sexually transmitted diseases, hides inside human cells using a cloaking mechanism to avoid detection and destruction.
The female genital tract can be a hostile environment for conception. Out of about 100 million sperm, only a few hundred make it to the fallopian tubes.
One out of every 500 to 1,000 boys is born with one or more extra X chromosomes, which can cause a variety of symptoms as the extra chromosomes to including infertility, larger breasts, osteoporosis, diabetes, cardiac problems, intellectual incapacity, and cancer.
We speak to Professor Charles Easley about his latest research into male infertility, and how sperm cells could be potentially developed from primate stem cells.
In this interview, we speak to Dr. Miguel J. Xavier about his latest research into male infertility and how de novo mutations may play a part.
Microtubules are fibers in cells that construct a network to offer shape and structure to cells along with mediating transport mechanisms.
Scientists at Cincinnati Children's appear to have flipped another piece in the underexplored puzzle of male infertility.
With global rates of male infertility continuing to rise, a new study in spermatogonial stem cell research led by researchers at the University of Georgia provides hope for future clinical therapies.
Nearly half of our DNA has been written off as junk, the discards of evolution: sidelined or broken genes, viruses that got stuck in our genome and were dismembered or silenced, none of it relevant to the human organism or human evolution.
Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells.
MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells.
Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.