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Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Enhancing Breast Cancer Therapy through Killing ‘Sleeper Cells’

AZoLifeSciences speaks to Dr. James Whittle and Professor Geoff Lindeman about their research in enhancing breast cancer therapy through killing sleeper cells.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 6 Aug 2020

Researchers discover genetic cause of severe auto inflammatory syndrome

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of--and a treatment for--a previously unknown severe auto inflam-matory syndrome affecting an 18-year-old girl since infancy.

5 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Study shows how psychological stress leads to debilitating vessel-clogging episodes

Researchers from the Albert Einstein College of Medicine have demonstrated that chronic psychological stress can result in painful vessel-clogging episodes—a frequent cause of hospitalizations and the most typical complication of sickle-cell disease or SCD.

31 Jul 2020

Rapid drug development yields potential treatment for yellow fever

Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths.

From Massachusetts Institute of Technology (MIT) 30 Jul 2020

Cholesterol-lowering medication improves function of the coronary arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

30 Jul 2020

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Analyses of lung fluid cells from COVID-19 patients conducted on a supercomputer point to patterns that may explain the body's response to SARS-CoV-2.

29 Jul 2020

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

AZoLifeSciences talks to Dr. Shane Liddelow about their research into discovering the critical role of astrocytes in neurodegenerative diseases like glaucoma.

From New York University (NYU) 29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

A protein found in viruses that are responsible for causing SARS and COVID-19 infections is virtually identical.

29 Jul 2020

Study validates new pharmacological target for Alzheimer’s disease

A UB study published in the journal Neurotherapeutics has validated a new pharmacological target for Alzheimer's disease.

28 Jul 2020

New study shows how T cells function in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

27 Jul 2020

Higher levels of specific protein linked with severity of COVID-19 symptoms

A new study found raised levels of transforming growth factor beta-induced protein (TGFBIp) in blood sampled from roughly 100 people hospitalized for COVID-19, and further found that elevated levels of both the normal and acetylated forms of TGFBIp correlated with the severity of disease symptoms in these patients.

27 Jul 2020