Inflammatory Bowel Disease News and Research

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Inflammatory bowel disease (IBD) is an ongoing or chronic health problem that causes inflammation and swelling in the digestive tract. The irritation causes bleeding sores called ulcers to form along the digestive tract. This in turn can cause crampy, abdominal pain and severe bloody diarrhea.

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Severe ulcerative colitis - a form of inflammatory bowel disease (IBD) - has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found.

From The University of New South Wales (UNSW) 30 Oct 2020

Cell therapy designed to treat inflammatory bowel disease

The results obtained are encouraging and the researchers could make headway in a multifunctional cell therapy system to treat inflammatory bowel disease.

29 Sep 2020

Polyphenolic compound extracted from blueberry can treat inflammatory bowel disease

Different plants and their products contain “bioactive” components that can reduce human diseases.

25 Sep 2020

Neuronal connections that trigger insomnia linked to stress-induced changes in the immune system

Scientists at Cold Spring Harbor Laboratory and Stanford University have pinpointed the circuit in the brain that is responsible for sleepless nights in times of stress--and it turns out that circuit does more than make you toss and turn.

10 Sep 2020

New cellular pathway can protect cells from infection by Ebola virus, coronavirus

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

25 Aug 2020

Chronic inflammation disrupts tissue structure of the colon, study finds

In a new study, researchers have compared diseased colon with healthy tissue to better understand how inflammatory bowel disease (IBD) is linked to an increased risk of colorectal cancers, at a molecular level.

22 Jul 2020

Combination of western-style high-fat diet with antibiotic can increase the risk of pre-IBD

Researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre- inflammatory bowel disease.

16 Jul 2020

Salk researchers discover genetic 'dial' to fine-tune the immune response

The human immune system is a finely-tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself.

8 Jul 2020

Study highlights the role of hematopoietic immune cells in gene regulation

More often, the human body is viewed as a “machine” containing specialized components: immune cells protect against pathogens, organs contribute physiological functions, and soft tissue and bones give structure.

6 Jul 2020

Foodborne titanium dioxide nanoparticles impact gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

26 Jun 2020

Understanding protein-coding gene's role in IBD

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

9 Jun 2020

New tool shows how microbes influence health and promote diseases

Scientists from the Quadram Institute and Earlham Institute have developed a unique tool that is helping them to translate the complex communication that takes place between the body and the microbiome.

25 May 2020

Uncovering How 'Dark Matter' Regions Of The Genome Affect Inflammatory Diseases

A study has uncovered how variations in a non-protein coding 'dark matter' region of the genome could make patients susceptible to complex autoimmune diseases.

14 May 2020

Junk food consumed by U.S. adults is associated with inflammatory bowel disease

Foods like cookies, cheese, soda, and French fries are often present in the diets of U.S. adults suffering from inflammatory bowel disease.

7 May 2020

MSC‐induced Treg population can yield abundant replacement for naturally occurring T-cells

A new study released today in STEM CELLS suggests for the first time that regulatory T-cells (Treg) induced by mesenchymal stromal cells can yield an abundant replacement for naturally occurring T-cells, which are vital in protecting the body from infection.

30 Apr 2020

Plant genes control microbiome diversity inside leaves to stay healthy

In a new study, published in the journal Nature, Michigan State University scientists show how plant genes select which microbes get to live inside their leaves in order to stay healthy.

14 Apr 2020

Important genetic mechanism behind inflammatory bowel disease revealed

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

10 Apr 2020

Multi-tissue model shows how different tissues account for various inflammatory diseases

Biological engineers from Massachusetts Institute of Technology (MIT) have developed a multi-tissue model that allows them to analyze the associations between the immune system and different organs, on a dedicated microfluidic platform embedded with human cells.

From Massachusetts Institute of Technology (MIT) 19 Mar 2020